Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789942754> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2789942754 endingPage "109" @default.
- W2789942754 startingPage "106" @default.
- W2789942754 abstract "Abstract In the present study the non invasive approach combining the small interference RNA (RNAi) based oncogenic suppression and silver nanoparticle (AgNP) effect to achieve efficient lung cancer combination therapeutics with minimal toxicity to normal lung cells was investigated. Direct electroporation technique was performed on both cancerous (A549) and normal lung (L132) cells targeting the AKT-1 gene expression. Interestingly the investigation showed significant down-regulation of AKT-1 siRNA gene expression by combined effect of AKT-siRNA and AgNP treatment in A549 cells when compared to their alone effect. Based on above findings and previous reports the plausible molecular mechanistic pathway was proposed. This study put further impetus in the development of nanotherapeutics combining AgNP and AKT-1 siRNA for efficient lung carcinoma treatment." @default.
- W2789942754 created "2018-03-29" @default.
- W2789942754 creator A5070286618 @default.
- W2789942754 creator A5080443477 @default.
- W2789942754 date "2018-04-01" @default.
- W2789942754 modified "2023-09-24" @default.
- W2789942754 title "Enhanced targeted anticancer potential of AKT-1 siRNA, an inhibitor of Protein Kinase B, in combination with silver nanoparticle against non-small cell lung adenocarcinoma" @default.
- W2789942754 cites W1840741300 @default.
- W2789942754 cites W1971888650 @default.
- W2789942754 cites W1972512448 @default.
- W2789942754 cites W2010585094 @default.
- W2789942754 cites W2039322848 @default.
- W2789942754 cites W2047017162 @default.
- W2789942754 cites W2054022416 @default.
- W2789942754 cites W2084953152 @default.
- W2789942754 cites W2086775675 @default.
- W2789942754 cites W2144766937 @default.
- W2789942754 cites W2171819216 @default.
- W2789942754 cites W2216239984 @default.
- W2789942754 cites W2461438546 @default.
- W2789942754 cites W2525675203 @default.
- W2789942754 cites W2556868827 @default.
- W2789942754 cites W2599525429 @default.
- W2789942754 cites W2605939533 @default.
- W2789942754 cites W2607282953 @default.
- W2789942754 cites W2738377689 @default.
- W2789942754 cites W2774316539 @default.
- W2789942754 doi "https://doi.org/10.1016/j.nanoso.2018.01.011" @default.
- W2789942754 hasPublicationYear "2018" @default.
- W2789942754 type Work @default.
- W2789942754 sameAs 2789942754 @default.
- W2789942754 citedByCount "4" @default.
- W2789942754 countsByYear W27899427542018 @default.
- W2789942754 countsByYear W27899427542019 @default.
- W2789942754 countsByYear W27899427542021 @default.
- W2789942754 crossrefType "journal-article" @default.
- W2789942754 hasAuthorship W2789942754A5070286618 @default.
- W2789942754 hasAuthorship W2789942754A5080443477 @default.
- W2789942754 hasConcept C11960822 @default.
- W2789942754 hasConcept C121608353 @default.
- W2789942754 hasConcept C126322002 @default.
- W2789942754 hasConcept C184235292 @default.
- W2789942754 hasConcept C185592680 @default.
- W2789942754 hasConcept C2781182431 @default.
- W2789942754 hasConcept C502942594 @default.
- W2789942754 hasConcept C55493867 @default.
- W2789942754 hasConcept C71924100 @default.
- W2789942754 hasConcept C75217442 @default.
- W2789942754 hasConceptScore W2789942754C11960822 @default.
- W2789942754 hasConceptScore W2789942754C121608353 @default.
- W2789942754 hasConceptScore W2789942754C126322002 @default.
- W2789942754 hasConceptScore W2789942754C184235292 @default.
- W2789942754 hasConceptScore W2789942754C185592680 @default.
- W2789942754 hasConceptScore W2789942754C2781182431 @default.
- W2789942754 hasConceptScore W2789942754C502942594 @default.
- W2789942754 hasConceptScore W2789942754C55493867 @default.
- W2789942754 hasConceptScore W2789942754C71924100 @default.
- W2789942754 hasConceptScore W2789942754C75217442 @default.
- W2789942754 hasFunder F4320326656 @default.
- W2789942754 hasFunder F4320334771 @default.
- W2789942754 hasLocation W27899427541 @default.
- W2789942754 hasOpenAccess W2789942754 @default.
- W2789942754 hasPrimaryLocation W27899427541 @default.
- W2789942754 hasRelatedWork W1973188327 @default.
- W2789942754 hasRelatedWork W2004253476 @default.
- W2789942754 hasRelatedWork W2077367078 @default.
- W2789942754 hasRelatedWork W2088269540 @default.
- W2789942754 hasRelatedWork W2118231005 @default.
- W2789942754 hasRelatedWork W2127721237 @default.
- W2789942754 hasRelatedWork W2222533714 @default.
- W2789942754 hasRelatedWork W2242217668 @default.
- W2789942754 hasRelatedWork W2944880966 @default.
- W2789942754 hasRelatedWork W2997668632 @default.
- W2789942754 hasVolume "14" @default.
- W2789942754 isParatext "false" @default.
- W2789942754 isRetracted "false" @default.
- W2789942754 magId "2789942754" @default.
- W2789942754 workType "article" @default.