FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2789959894> ?p ?o ?g. }

• W2789959894 endingPage "937" @default.
• W2789959894 startingPage "931" @default.
• W2789959894 abstract "Background and Purpose— Ipsilateral thalamic diaschisis (ITD) describes the reduction of thalamic function, metabolism, and perfusion resulting from a distant lesion of the ipsilateral hemisphere. Our aim was to evaluate the perfusion characteristics and clinical impact of ITD in acute middle cerebral artery stroke, which does not directly affect the thalamus. Methods— One hundred twenty-four patients with middle cerebral artery infarction were selected from a prospectively acquired cohort of 1644 patients who underwent multiparametric computed tomography (CT), including CT perfusion for suspected stroke. Two blinded readers evaluated the occurrence of ITD, defined as ipsilateral thalamic hypoperfusion present on ≥2 CT perfusion maps. Perfusion alterations were defined according to the Alberta Stroke Program Early CT Score regions. Final infarction volume and subacute complications were assessed on follow-up imaging. Clinical outcome was quantified using the modified Rankin Scale. Multivariable linear and ordinal logistic regression analysis were applied to identify independent associations. Results— ITD was present in 25/124 subjects (20.2%, ITD+). In ITD+ subjects, perfusion of the caudate nucleus, internal capsule, and lentiform nucleus was more frequently affected than in ITD− patients (each with P <0.001). In the ITD+ group, larger cerebral blood flow ( P =0.002) and cerebral blood volume ( P <0.001) deficit volumes, as well as smaller cerebral blood flow–cerebral blood volume mismatch ( P =0.021) were observed. There was no independent association of ITD with final infarction volume or clinical outcome at discharge in treatment subgroups (each with P >0.05). ITD had no influence on the development of subacute stroke complications. Conclusions— ITD in the form of thalamic hypoperfusion is a frequent CT perfusion finding in the acute phase in middle cerebral artery stroke patients with marked involvement of subcortical areas. ITD does not result in thalamic infarction and had no independent impact on patient outcome. Notably, ITD was misclassified as part of the ischemic core by automated software, which might affect patient selection in CT perfusion–based trials." @default.
• W2789959894 created "2018-03-29" @default.
• W2789959894 creator A5000710078 @default.
• W2789959894 creator A5011186852 @default.
• W2789959894 creator A5012317748 @default.
• W2789959894 creator A5037704473 @default.
• W2789959894 creator A5065429336 @default.
• W2789959894 creator A5068808600 @default.
• W2789959894 creator A5071803972 @default.
• W2789959894 creator A5077921096 @default.
• W2789959894 creator A5088588603 @default.
• W2789959894 date "2018-04-01" @default.
• W2789959894 modified "2023-10-18" @default.
• W2789959894 title "Thalamic Diaschisis in Acute Ischemic Stroke" @default.
• W2789959894 cites W1582061507 @default.
• W2789959894 cites W1988023627 @default.
• W2789959894 cites W2010123464 @default.
• W2789959894 cites W2010865726 @default.
• W2789959894 cites W2020317679 @default.
• W2789959894 cites W2022885408 @default.
• W2789959894 cites W2036035699 @default.
• W2789959894 cites W2056420047 @default.
• W2789959894 cites W2082641523 @default.
• W2789959894 cites W2091033081 @default.
• W2789959894 cites W2103704226 @default.
• W2789959894 cites W2111707360 @default.
• W2789959894 cites W2112754040 @default.
• W2789959894 cites W2116189614 @default.
• W2789959894 cites W2131504507 @default.
• W2789959894 cites W2134155886 @default.
• W2789959894 cites W2139382992 @default.
• W2789959894 cites W2140442139 @default.
• W2789959894 cites W2164747888 @default.
• W2789959894 cites W2168321439 @default.
• W2789959894 cites W2317325433 @default.
• W2789959894 cites W2332265046 @default.
• W2789959894 cites W2346476075 @default.
• W2789959894 cites W2730861989 @default.
• W2789959894 cites W2767776410 @default.
• W2789959894 cites W2787867590 @default.
• W2789959894 cites W4255683973 @default.
• W2789959894 doi "https://doi.org/10.1161/strokeaha.118.020698" @default.
• W2789959894 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29523650" @default.
• W2789959894 hasPublicationYear "2018" @default.
• W2789959894 type Work @default.
• W2789959894 sameAs 2789959894 @default.
• W2789959894 citedByCount "20" @default.
• W2789959894 countsByYear W27899598942019 @default.
• W2789959894 countsByYear W27899598942020 @default.
• W2789959894 countsByYear W27899598942021 @default.
• W2789959894 countsByYear W27899598942022 @default.
• W2789959894 countsByYear W27899598942023 @default.
• W2789959894 crossrefType "journal-article" @default.
• W2789959894 hasAuthorship W2789959894A5000710078 @default.
• W2789959894 hasAuthorship W2789959894A5011186852 @default.
• W2789959894 hasAuthorship W2789959894A5012317748 @default.
• W2789959894 hasAuthorship W2789959894A5037704473 @default.
• W2789959894 hasAuthorship W2789959894A5065429336 @default.
• W2789959894 hasAuthorship W2789959894A5068808600 @default.
• W2789959894 hasAuthorship W2789959894A5071803972 @default.
• W2789959894 hasAuthorship W2789959894A5077921096 @default.
• W2789959894 hasAuthorship W2789959894A5088588603 @default.
• W2789959894 hasBestOaLocation W27899598941 @default.
• W2789959894 hasConcept C126322002 @default.
• W2789959894 hasConcept C126838900 @default.
• W2789959894 hasConcept C127413603 @default.
• W2789959894 hasConcept C135691158 @default.
• W2789959894 hasConcept C146957229 @default.
• W2789959894 hasConcept C154281038 @default.
• W2789959894 hasConcept C157767197 @default.
• W2789959894 hasConcept C164705383 @default.
• W2789959894 hasConcept C2775841333 @default.
• W2789959894 hasConcept C2777798775 @default.
• W2789959894 hasConcept C2778095648 @default.
• W2789959894 hasConcept C2779652256 @default.
• W2789959894 hasConcept C2780645631 @default.
• W2789959894 hasConcept C500558357 @default.
• W2789959894 hasConcept C541997718 @default.
• W2789959894 hasConcept C71924100 @default.
• W2789959894 hasConcept C78519656 @default.
• W2789959894 hasConceptScore W2789959894C126322002 @default.
• W2789959894 hasConceptScore W2789959894C126838900 @default.
• W2789959894 hasConceptScore W2789959894C127413603 @default.
• W2789959894 hasConceptScore W2789959894C135691158 @default.
• W2789959894 hasConceptScore W2789959894C146957229 @default.
• W2789959894 hasConceptScore W2789959894C154281038 @default.
• W2789959894 hasConceptScore W2789959894C157767197 @default.
• W2789959894 hasConceptScore W2789959894C164705383 @default.
• W2789959894 hasConceptScore W2789959894C2775841333 @default.
• W2789959894 hasConceptScore W2789959894C2777798775 @default.
• W2789959894 hasConceptScore W2789959894C2778095648 @default.
• W2789959894 hasConceptScore W2789959894C2779652256 @default.
• W2789959894 hasConceptScore W2789959894C2780645631 @default.
• W2789959894 hasConceptScore W2789959894C500558357 @default.
• W2789959894 hasConceptScore W2789959894C541997718 @default.
• W2789959894 hasConceptScore W2789959894C71924100 @default.
• W2789959894 hasConceptScore W2789959894C78519656 @default.
• W2789959894 hasIssue "4" @default.

• next