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- W2790150526 abstract "Pediatric brain tumors (PBTs) are the most common solid malignancies in childhood and continue to pose a serious burden to modern societies. Existing treatments impose debilitating effects on the developing child, highlighting the need for molecularly targeted treatments with reduced toxicity, as well as the necessity of markers that reliably assess efficacy of, and tumor response to targeted-therapies of PBTs. On this regard advances in technologies of protein identification and quantification, the large-scale, high-throughput investigation of the proteome, as well the newly-emerging field of proteogenomics aim to further our knowledge towards understanding the molecular pathophysiology of PBTs. This mini review article presents all updates on knowledge produced and published during the last years on PBT research derived from omics technologies, mainly involving protein research and proteomics." @default.
- W2790150526 created "2018-03-29" @default.
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- W2790150526 date "2018-09-01" @default.
- W2790150526 modified "2023-09-23" @default.
- W2790150526 title "Pediatric brain tumors: Update of proteome-based studies" @default.
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- W2790150526 doi "https://doi.org/10.1016/j.jprot.2018.02.016" @default.
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