Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790194277> ?p ?o ?g. }
- W2790194277 abstract "Abstract Time–concentration curves for the topical anti‐viral drug acyclovir can provide valuable information for drug development. Open flow microperfusion is used for continuous sampling of dermal interstitial fluid but it requires validated methods for subsequent sample analysis. Therefore, we developed a sensitive, selective and high‐throughput ultra‐high‐performance liquid chromatography–high‐resolution tandem mass spectrometry method to determine acyclovir in human dermal interstitial fluid and serum. We validated the method over a concentration range of 0.1–25 ng/mL for a sample volume of just 20 μL and employed cation‐exchange solid‐phase extraction in a fully automated sample treatment procedure. Short‐ and long‐term sample stability data and the analysis of 5000 samples from a clinical trial demonstrate the successful application of our method." @default.
- W2790194277 created "2018-03-29" @default.
- W2790194277 creator A5002136055 @default.
- W2790194277 creator A5025178104 @default.
- W2790194277 creator A5028528336 @default.
- W2790194277 creator A5090737349 @default.
- W2790194277 creator A5091116033 @default.
- W2790194277 date "2018-02-27" @default.
- W2790194277 modified "2023-09-27" @default.
- W2790194277 title "Quantification of acyclovir in dermal interstitial fluid and human serum by ultra-high-performance liquid-high-resolution tandem mass spectrometry for topical bioequivalence evaluation" @default.
- W2790194277 cites W1898884874 @default.
- W2790194277 cites W1970729158 @default.
- W2790194277 cites W1976209099 @default.
- W2790194277 cites W1984779552 @default.
- W2790194277 cites W1991145576 @default.
- W2790194277 cites W1997527498 @default.
- W2790194277 cites W2012081361 @default.
- W2790194277 cites W2017205053 @default.
- W2790194277 cites W2028497247 @default.
- W2790194277 cites W2031929695 @default.
- W2790194277 cites W2061847396 @default.
- W2790194277 cites W2064847412 @default.
- W2790194277 cites W2072330286 @default.
- W2790194277 cites W2074817486 @default.
- W2790194277 cites W2076294501 @default.
- W2790194277 cites W2078245554 @default.
- W2790194277 cites W2092121604 @default.
- W2790194277 cites W2092725953 @default.
- W2790194277 cites W2100093895 @default.
- W2790194277 cites W2166701245 @default.
- W2790194277 cites W2258164121 @default.
- W2790194277 cites W2515414172 @default.
- W2790194277 cites W649209898 @default.
- W2790194277 doi "https://doi.org/10.1002/bmc.4194" @default.
- W2790194277 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29349796" @default.
- W2790194277 hasPublicationYear "2018" @default.
- W2790194277 type Work @default.
- W2790194277 sameAs 2790194277 @default.
- W2790194277 citedByCount "9" @default.
- W2790194277 countsByYear W27901942772018 @default.
- W2790194277 countsByYear W27901942772019 @default.
- W2790194277 countsByYear W27901942772021 @default.
- W2790194277 countsByYear W27901942772022 @default.
- W2790194277 crossrefType "journal-article" @default.
- W2790194277 hasAuthorship W2790194277A5002136055 @default.
- W2790194277 hasAuthorship W2790194277A5025178104 @default.
- W2790194277 hasAuthorship W2790194277A5028528336 @default.
- W2790194277 hasAuthorship W2790194277A5090737349 @default.
- W2790194277 hasAuthorship W2790194277A5091116033 @default.
- W2790194277 hasConcept C112705442 @default.
- W2790194277 hasConcept C127313418 @default.
- W2790194277 hasConcept C138268822 @default.
- W2790194277 hasConcept C154945302 @default.
- W2790194277 hasConcept C159985019 @default.
- W2790194277 hasConcept C162356407 @default.
- W2790194277 hasConcept C185592680 @default.
- W2790194277 hasConcept C192562407 @default.
- W2790194277 hasConcept C2777814067 @default.
- W2790194277 hasConcept C2778576202 @default.
- W2790194277 hasConcept C3020199158 @default.
- W2790194277 hasConcept C31827203 @default.
- W2790194277 hasConcept C41008148 @default.
- W2790194277 hasConcept C42404028 @default.
- W2790194277 hasConcept C43617362 @default.
- W2790194277 hasConcept C62649853 @default.
- W2790194277 hasConcept C64489805 @default.
- W2790194277 hasConcept C71924100 @default.
- W2790194277 hasConcept C81426234 @default.
- W2790194277 hasConcept C98274493 @default.
- W2790194277 hasConceptScore W2790194277C112705442 @default.
- W2790194277 hasConceptScore W2790194277C127313418 @default.
- W2790194277 hasConceptScore W2790194277C138268822 @default.
- W2790194277 hasConceptScore W2790194277C154945302 @default.
- W2790194277 hasConceptScore W2790194277C159985019 @default.
- W2790194277 hasConceptScore W2790194277C162356407 @default.
- W2790194277 hasConceptScore W2790194277C185592680 @default.
- W2790194277 hasConceptScore W2790194277C192562407 @default.
- W2790194277 hasConceptScore W2790194277C2777814067 @default.
- W2790194277 hasConceptScore W2790194277C2778576202 @default.
- W2790194277 hasConceptScore W2790194277C3020199158 @default.
- W2790194277 hasConceptScore W2790194277C31827203 @default.
- W2790194277 hasConceptScore W2790194277C41008148 @default.
- W2790194277 hasConceptScore W2790194277C42404028 @default.
- W2790194277 hasConceptScore W2790194277C43617362 @default.
- W2790194277 hasConceptScore W2790194277C62649853 @default.
- W2790194277 hasConceptScore W2790194277C64489805 @default.
- W2790194277 hasConceptScore W2790194277C71924100 @default.
- W2790194277 hasConceptScore W2790194277C81426234 @default.
- W2790194277 hasConceptScore W2790194277C98274493 @default.
- W2790194277 hasFunder F4320332163 @default.
- W2790194277 hasIssue "6" @default.
- W2790194277 hasLocation W27901942771 @default.
- W2790194277 hasLocation W27901942772 @default.
- W2790194277 hasOpenAccess W2790194277 @default.
- W2790194277 hasPrimaryLocation W27901942771 @default.
- W2790194277 hasRelatedWork W2003507098 @default.
- W2790194277 hasRelatedWork W2004208954 @default.
- W2790194277 hasRelatedWork W2004413746 @default.
- W2790194277 hasRelatedWork W2008161654 @default.
- W2790194277 hasRelatedWork W2028520241 @default.