FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790258757> ?p ?o ?g. }

• W2790258757 abstract "Pre-exposure prophylaxis (PrEP) with antiretrovirals is an efficacious and effective intervention to decrease the risk of HIV (human immunodeficiency virus) acquisition. Yet drug and delivery costs prohibit access in many jurisdictions. In the absence of guidelines for the synthesis of economic evaluations, we developed a protocol for a systematic review of economic evaluation studies for PrEP by drawing on best practices in systematic reviews and the conduct and reporting of economic evaluations. We aim to estimate the incremental cost per health outcome of PrEP compared with placebo, no PrEP, or other HIV prevention strategies; assess the methodological variability in, and quality of, economic evaluations of PrEP; estimate the incremental cost per health outcome of different PrEP implementation strategies; and quantify the potential sources of heterogeneity in outcomes.We will systematically search electronic databases (MEDLINE, Embase) and the gray literature. We will include economic evaluation studies that assess both costs and health outcomes of PrEP in HIV-uninfected individuals, without restricting language or year of publication. Two reviewers will independently screen studies using predefined inclusion criteria, extract data, and assess methodological quality using the Philips checklist, Second Panel on the Cost-effectiveness of Health and Medicines, and the International Society for Pharmacoeconomics and Outcomes Research recommendations. Outcomes of interest include incremental costs and outcomes in natural units or utilities, cost-effectiveness ratios, and net monetary benefit. We will perform descriptive and quantitative syntheses using sensitivity analyses of outcomes by population subgroups, HIV epidemic settings, study designs, baseline intervention contexts, key parameter inputs and assumptions, type of outcomes, economic perspectives, and willingness to pay values.Findings will guide future economic evaluation of PrEP strategies in terms of methodological and knowledge gaps, and will inform decisions on the efficient integration of PrEP into public health programs across epidemiologic and health system contexts.PROSPERO CRD42016038440 ." @default.
• W2790258757 created "2018-03-29" @default.
• W2790258757 creator A5001052807 @default.
• W2790258757 creator A5010749025 @default.
• W2790258757 creator A5016285458 @default.
• W2790258757 creator A5023448131 @default.
• W2790258757 creator A5065930021 @default.
• W2790258757 creator A5078027320 @default.
• W2790258757 creator A5078051381 @default.
• W2790258757 creator A5085526562 @default.
• W2790258757 creator A5090773947 @default.
• W2790258757 date "2018-03-15" @default.
• W2790258757 modified "2023-09-26" @default.
• W2790258757 title "Economic evaluation of HIV pre-exposure prophylaxis strategies: protocol for a methodological systematic review and quantitative synthesis" @default.
• W2790258757 cites W1590860156 @default.
• W2790258757 cites W1973090847 @default.
• W2790258757 cites W2026063780 @default.
• W2790258757 cites W2037809152 @default.
• W2790258757 cites W2060513754 @default.
• W2790258757 cites W2065159982 @default.
• W2790258757 cites W2081270036 @default.
• W2790258757 cites W2094145886 @default.
• W2790258757 cites W2097031922 @default.
• W2790258757 cites W2098803196 @default.
• W2790258757 cites W2123519394 @default.
• W2790258757 cites W2131553265 @default.
• W2790258757 cites W2142704172 @default.
• W2790258757 cites W2161107069 @default.
• W2790258757 cites W2161374186 @default.
• W2790258757 cites W2171310617 @default.
• W2790258757 cites W2184589485 @default.
• W2790258757 cites W2345950548 @default.
• W2790258757 cites W2395668774 @default.
• W2790258757 cites W2415454735 @default.
• W2790258757 cites W2462783594 @default.
• W2790258757 cites W2519603001 @default.
• W2790258757 cites W2523631564 @default.
• W2790258757 cites W2532434394 @default.
• W2790258757 cites W2537318543 @default.
• W2790258757 cites W2610309560 @default.
• W2790258757 cites W2620199044 @default.
• W2790258757 cites W2621066980 @default.
• W2790258757 cites W2622673596 @default.
• W2790258757 cites W2742089017 @default.
• W2790258757 cites W2752732259 @default.
• W2790258757 cites W3143265745 @default.
• W2790258757 cites W3203717762 @default.
• W2790258757 cites W4232311869 @default.
• W2790258757 doi "https://doi.org/10.1186/s13643-018-0710-0" @default.
• W2790258757 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5855998" @default.
• W2790258757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29544530" @default.
• W2790258757 hasPublicationYear "2018" @default.
• W2790258757 type Work @default.
• W2790258757 sameAs 2790258757 @default.
• W2790258757 citedByCount "1" @default.
• W2790258757 countsByYear W27902587572023 @default.
• W2790258757 crossrefType "journal-article" @default.
• W2790258757 hasAuthorship W2790258757A5001052807 @default.
• W2790258757 hasAuthorship W2790258757A5010749025 @default.
• W2790258757 hasAuthorship W2790258757A5016285458 @default.
• W2790258757 hasAuthorship W2790258757A5023448131 @default.
• W2790258757 hasAuthorship W2790258757A5065930021 @default.
• W2790258757 hasAuthorship W2790258757A5078027320 @default.
• W2790258757 hasAuthorship W2790258757A5078051381 @default.
• W2790258757 hasAuthorship W2790258757A5085526562 @default.
• W2790258757 hasAuthorship W2790258757A5090773947 @default.
• W2790258757 hasBestOaLocation W27902587571 @default.
• W2790258757 hasConcept C112930515 @default.
• W2790258757 hasConcept C127454912 @default.
• W2790258757 hasConcept C142724271 @default.
• W2790258757 hasConcept C15744967 @default.
• W2790258757 hasConcept C159110408 @default.
• W2790258757 hasConcept C160735492 @default.
• W2790258757 hasConcept C162324750 @default.
• W2790258757 hasConcept C17744445 @default.
• W2790258757 hasConcept C177713679 @default.
• W2790258757 hasConcept C180747234 @default.
• W2790258757 hasConcept C18903297 @default.
• W2790258757 hasConcept C189708586 @default.
• W2790258757 hasConcept C199539241 @default.
• W2790258757 hasConcept C204787440 @default.
• W2790258757 hasConcept C27415008 @default.
• W2790258757 hasConcept C2776125615 @default.
• W2790258757 hasConcept C2776738588 @default.
• W2790258757 hasConcept C2776939746 @default.
• W2790258757 hasConcept C2776983459 @default.
• W2790258757 hasConcept C2779356329 @default.
• W2790258757 hasConcept C2779473830 @default.
• W2790258757 hasConcept C2779496540 @default.
• W2790258757 hasConcept C2780385302 @default.
• W2790258757 hasConcept C2908647359 @default.
• W2790258757 hasConcept C3013748606 @default.
• W2790258757 hasConcept C3019080777 @default.
• W2790258757 hasConcept C50522688 @default.
• W2790258757 hasConcept C512399662 @default.
• W2790258757 hasConcept C71924100 @default.
• W2790258757 hasConcept C86803240 @default.
• W2790258757 hasConcept C95190672 @default.
• W2790258757 hasConcept C99454951 @default.
• W2790258757 hasConceptScore W2790258757C112930515 @default.

• next