FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790504505> ?p ?o ?g. }

• W2790504505 endingPage "2345" @default.
• W2790504505 startingPage "2336" @default.
• W2790504505 abstract "Abstract Context Patients with congenital adrenal hyperplasia (CAH) are at risk for life-threatening adrenal crises. Management of illness episodes aims to prevent adrenal crises. Objective We evaluated rates of illnesses and associated factors in patients with CAH followed prospectively and receiving repeated glucocorticoid stress dosing education. Methods Longitudinal analysis of 156 patients with CAH followed at the National Institutes of Health Clinical Center over 23 years was performed. The rates of illnesses and stress-dose days, emergency room (ER) visits, hospitalizations, and adrenal crises were analyzed in relation to phenotype, age, sex, treatment, and hormonal evaluations. Results A total of 2298 visits were evaluated. Patients were followed for 9.3 ± 6.0 years. During childhood, there were more illness episodes and stress dosing than adulthood (P &lt; 0.001); however, more ER visits and hospitalizations occurred during adulthood (P ≤ 0.03). The most robust predictors of stress dosing were young age, low hydrocortisone and high fludrocortisone dose during childhood, and female sex during adulthood. Gastrointestinal and upper respiratory tract infections (URIs) were the two most common precipitating events for adrenal crises and hospitalizations across all ages. Adrenal crisis with probable hypoglycemia occurred in 11 pediatric patients (ages 1.1 to 11.3 years). Undetectable epinephrine was associated with ER visits during childhood (P = 0.03) and illness episodes during adulthood (P = 0.03). Conclusions Repeated stress-related glucocorticoid dosing teaching is essential, but revised age-appropriate guidelines for the management of infectious illnesses are needed for patients with adrenal insufficiency that aim to reduce adrenal crises and prevent hypoglycemia, particularly in children." @default.
• W2790504505 created "2018-03-29" @default.
• W2790504505 creator A5018267559 @default.
• W2790504505 creator A5021756024 @default.
• W2790504505 creator A5044873897 @default.
• W2790504505 creator A5049689973 @default.
• W2790504505 creator A5053315211 @default.
• W2790504505 creator A5089565121 @default.
• W2790504505 date "2018-03-22" @default.
• W2790504505 modified "2023-10-15" @default.
• W2790504505 title "Longitudinal Assessment of Illnesses, Stress Dosing, and Illness Sequelae in Patients With Congenital Adrenal Hyperplasia" @default.
• W2790504505 cites W1891265483 @default.
• W2790504505 cites W1964051953 @default.
• W2790504505 cites W1972087695 @default.
• W2790504505 cites W1976145935 @default.
• W2790504505 cites W1977128264 @default.
• W2790504505 cites W1991990426 @default.
• W2790504505 cites W1993728185 @default.
• W2790504505 cites W2034465739 @default.
• W2790504505 cites W2068255620 @default.
• W2790504505 cites W2073726358 @default.
• W2790504505 cites W2089955349 @default.
• W2790504505 cites W2102975934 @default.
• W2790504505 cites W2107621783 @default.
• W2790504505 cites W2113107736 @default.
• W2790504505 cites W2117425767 @default.
• W2790504505 cites W2128532760 @default.
• W2790504505 cites W2132382547 @default.
• W2790504505 cites W2134401266 @default.
• W2790504505 cites W2140875330 @default.
• W2790504505 cites W2148763233 @default.
• W2790504505 cites W2149437278 @default.
• W2790504505 cites W2152707359 @default.
• W2790504505 cites W2156366896 @default.
• W2790504505 cites W2161244872 @default.
• W2790504505 cites W2174340542 @default.
• W2790504505 cites W2230392972 @default.
• W2790504505 cites W2234917292 @default.
• W2790504505 cites W2279064379 @default.
• W2790504505 cites W2519685034 @default.
• W2790504505 cites W2524670571 @default.
• W2790504505 cites W2562904997 @default.
• W2790504505 cites W2567470960 @default.
• W2790504505 cites W2580792129 @default.
• W2790504505 cites W2588879072 @default.
• W2790504505 cites W2754015935 @default.
• W2790504505 doi "https://doi.org/10.1210/jc.2018-00208" @default.
• W2790504505 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6276663" @default.
• W2790504505 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29584889" @default.
• W2790504505 hasPublicationYear "2018" @default.
• W2790504505 type Work @default.
• W2790504505 sameAs 2790504505 @default.
• W2790504505 citedByCount "44" @default.
• W2790504505 countsByYear W27905045052018 @default.
• W2790504505 countsByYear W27905045052019 @default.
• W2790504505 countsByYear W27905045052020 @default.
• W2790504505 countsByYear W27905045052021 @default.
• W2790504505 countsByYear W27905045052022 @default.
• W2790504505 countsByYear W27905045052023 @default.
• W2790504505 crossrefType "journal-article" @default.
• W2790504505 hasAuthorship W2790504505A5018267559 @default.
• W2790504505 hasAuthorship W2790504505A5021756024 @default.
• W2790504505 hasAuthorship W2790504505A5044873897 @default.
• W2790504505 hasAuthorship W2790504505A5049689973 @default.
• W2790504505 hasAuthorship W2790504505A5053315211 @default.
• W2790504505 hasAuthorship W2790504505A5089565121 @default.
• W2790504505 hasBestOaLocation W27905045051 @default.
• W2790504505 hasConcept C126322002 @default.
• W2790504505 hasConcept C151730666 @default.
• W2790504505 hasConcept C187212893 @default.
• W2790504505 hasConcept C205545832 @default.
• W2790504505 hasConcept C2776899810 @default.
• W2790504505 hasConcept C2777288759 @default.
• W2790504505 hasConcept C2777767042 @default.
• W2790504505 hasConcept C2778129406 @default.
• W2790504505 hasConcept C2778709874 @default.
• W2790504505 hasConcept C2778808452 @default.
• W2790504505 hasConcept C2779306644 @default.
• W2790504505 hasConcept C2779343474 @default.
• W2790504505 hasConcept C2780668416 @default.
• W2790504505 hasConcept C2780841215 @default.
• W2790504505 hasConcept C71924100 @default.
• W2790504505 hasConcept C86803240 @default.
• W2790504505 hasConceptScore W2790504505C126322002 @default.
• W2790504505 hasConceptScore W2790504505C151730666 @default.
• W2790504505 hasConceptScore W2790504505C187212893 @default.
• W2790504505 hasConceptScore W2790504505C205545832 @default.
• W2790504505 hasConceptScore W2790504505C2776899810 @default.
• W2790504505 hasConceptScore W2790504505C2777288759 @default.
• W2790504505 hasConceptScore W2790504505C2777767042 @default.
• W2790504505 hasConceptScore W2790504505C2778129406 @default.
• W2790504505 hasConceptScore W2790504505C2778709874 @default.
• W2790504505 hasConceptScore W2790504505C2778808452 @default.
• W2790504505 hasConceptScore W2790504505C2779306644 @default.
• W2790504505 hasConceptScore W2790504505C2779343474 @default.
• W2790504505 hasConceptScore W2790504505C2780668416 @default.
• W2790504505 hasConceptScore W2790504505C2780841215 @default.
• W2790504505 hasConceptScore W2790504505C71924100 @default.

• next