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• W2790607524 abstract "This study aimed to investigate the effects of probiotics and clay detoxifier on the growth performance, enterotoxigenic bacteria and endotoxins, mucosal barrier, and visceral lesions of broilers fed diets contaminated with aflatoxin B1 (AFB1). One-day-old Arbor Acres broilers (n = 480) were randomly allocated into 4 groups with 6 replicates of 20 chicks each. Treatments included control, AFB1 (40 μg/kg), probiotics (AFB1 + probiotics 3 × 1010 cfu/kg), and clay (AFB1 + clay 3.0 g/kg). The trial lasted for 21 days. Results showed that AFB1 depressed (P < 0.05) feed intake and body weight gain, and the probiotics and clay detoxifier recovered (P < 0.05) the growth performance. Also, the AFB1 increased (P < 0.05) ileal counts of Clostridium perfringen, Escherichia coli, and Gram-negative bacteria, serum endotoxin and diamine oxidase, and hepatic and intestinal lesions, but decreased (P < 0.05) jejunal mRNA expressions of claudin-1, secretory IgA, and polymeric Ig receptors. Both probiotics and clay detoxifier ameliorated (P < 0.05) these negative effects, except the effects of clay detoxifier on Clostridium perfringen count and intestinal lesion scores, and the beneficial effect of probiotics was greater than that of clay detoxifier. The results suggest that the probiotics are capable of restoring growth performance and ameliorating enterotoxicity in broilers fed diets with AFB1 contamination." @default.
• W2790607524 created "2018-03-29" @default.
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• W2790607524 date "2018-09-01" @default.
• W2790607524 modified "2023-10-18" @default.
• W2790607524 title "Comparison of probiotics and clay detoxifier on the growth performance and enterotoxic markers of broilers fed diets contaminated with aflatoxin B1" @default.
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• W2790607524 doi "https://doi.org/10.3382/japr/pfy003" @default.
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