Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790607534> ?p ?o ?g. }
- W2790607534 endingPage "7" @default.
- W2790607534 startingPage "1" @default.
- W2790607534 abstract "To investigate the expression of HOX transcript antisense RNA (HOTAIR) in cardiac tissues and plasma of patients with congenital heart diseases (CHDs).qRT-PCR was used to detect the expression of HOTAIR in right atrial appendage tissues of 16 patients with CHDs and 14 patients with rheumatic valvular heart diseases (RVHDs), as well as in plasma of 36 normal people and 90 patients with CHDs including 36 cases of ASD, 23 cases of VSD, and 31 cases of PDA. Besides, the proteins interacting with HOTAIR were obtained from databases.The HOTAIR expression in cardiac tissues of CHDs group was significantly higher than that of the RVHDs group (P < 0.01). Compared with the control group, the expression of plasma HOTAIR in the ASD group, the VSD group, and the PDA group was all remarkably upregulated (P < 0.01), whereas there was no relationship between HOTAIR and pulmonary arterial hypertension and defects size. Databases show that HOTAIR is associated with polycomb repressive complex 2 (PRC2) which contributes to heart development.The levels of HOTAIR were increased in cardiac tissues and plasma of patients with CHDs. HOTAIR is a potential novel diagnostic biomarker in patients with CHDs." @default.
- W2790607534 created "2018-03-29" @default.
- W2790607534 creator A5023564768 @default.
- W2790607534 creator A5026569798 @default.
- W2790607534 creator A5038721944 @default.
- W2790607534 creator A5055006347 @default.
- W2790607534 creator A5066525650 @default.
- W2790607534 creator A5080723807 @default.
- W2790607534 creator A5084581807 @default.
- W2790607534 date "2018-01-01" @default.
- W2790607534 modified "2023-10-11" @default.
- W2790607534 title "HOTAIR Is a Potential Novel Biomarker in Patients with Congenital Heart Diseases" @default.
- W2790607534 cites W169467099 @default.
- W2790607534 cites W1976391453 @default.
- W2790607534 cites W1984191185 @default.
- W2790607534 cites W1989457690 @default.
- W2790607534 cites W2033478449 @default.
- W2790607534 cites W2086507603 @default.
- W2790607534 cites W2090034892 @default.
- W2790607534 cites W2092713090 @default.
- W2790607534 cites W2097549236 @default.
- W2790607534 cites W2097934124 @default.
- W2790607534 cites W2100982253 @default.
- W2790607534 cites W2125571324 @default.
- W2790607534 cites W2126504590 @default.
- W2790607534 cites W2146573461 @default.
- W2790607534 cites W2157512257 @default.
- W2790607534 cites W2159263860 @default.
- W2790607534 cites W2275702069 @default.
- W2790607534 cites W2319288043 @default.
- W2790607534 cites W2435647547 @default.
- W2790607534 cites W2519616827 @default.
- W2790607534 cites W2594950847 @default.
- W2790607534 cites W964275744 @default.
- W2790607534 doi "https://doi.org/10.1155/2018/2850657" @default.
- W2790607534 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5863312" @default.
- W2790607534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29707567" @default.
- W2790607534 hasPublicationYear "2018" @default.
- W2790607534 type Work @default.
- W2790607534 sameAs 2790607534 @default.
- W2790607534 citedByCount "26" @default.
- W2790607534 countsByYear W27906075342018 @default.
- W2790607534 countsByYear W27906075342019 @default.
- W2790607534 countsByYear W27906075342020 @default.
- W2790607534 countsByYear W27906075342021 @default.
- W2790607534 countsByYear W27906075342022 @default.
- W2790607534 countsByYear W27906075342023 @default.
- W2790607534 crossrefType "journal-article" @default.
- W2790607534 hasAuthorship W2790607534A5023564768 @default.
- W2790607534 hasAuthorship W2790607534A5026569798 @default.
- W2790607534 hasAuthorship W2790607534A5038721944 @default.
- W2790607534 hasAuthorship W2790607534A5055006347 @default.
- W2790607534 hasAuthorship W2790607534A5066525650 @default.
- W2790607534 hasAuthorship W2790607534A5080723807 @default.
- W2790607534 hasAuthorship W2790607534A5084581807 @default.
- W2790607534 hasBestOaLocation W27906075341 @default.
- W2790607534 hasConcept C104317684 @default.
- W2790607534 hasConcept C111039654 @default.
- W2790607534 hasConcept C126322002 @default.
- W2790607534 hasConcept C127561419 @default.
- W2790607534 hasConcept C150194340 @default.
- W2790607534 hasConcept C2776915012 @default.
- W2790607534 hasConcept C2781128886 @default.
- W2790607534 hasConcept C2781197716 @default.
- W2790607534 hasConcept C50171091 @default.
- W2790607534 hasConcept C502942594 @default.
- W2790607534 hasConcept C54355233 @default.
- W2790607534 hasConcept C62203573 @default.
- W2790607534 hasConcept C71924100 @default.
- W2790607534 hasConcept C86803240 @default.
- W2790607534 hasConceptScore W2790607534C104317684 @default.
- W2790607534 hasConceptScore W2790607534C111039654 @default.
- W2790607534 hasConceptScore W2790607534C126322002 @default.
- W2790607534 hasConceptScore W2790607534C127561419 @default.
- W2790607534 hasConceptScore W2790607534C150194340 @default.
- W2790607534 hasConceptScore W2790607534C2776915012 @default.
- W2790607534 hasConceptScore W2790607534C2781128886 @default.
- W2790607534 hasConceptScore W2790607534C2781197716 @default.
- W2790607534 hasConceptScore W2790607534C50171091 @default.
- W2790607534 hasConceptScore W2790607534C502942594 @default.
- W2790607534 hasConceptScore W2790607534C54355233 @default.
- W2790607534 hasConceptScore W2790607534C62203573 @default.
- W2790607534 hasConceptScore W2790607534C71924100 @default.
- W2790607534 hasConceptScore W2790607534C86803240 @default.
- W2790607534 hasFunder F4320312270 @default.
- W2790607534 hasLocation W27906075341 @default.
- W2790607534 hasLocation W27906075342 @default.
- W2790607534 hasLocation W27906075343 @default.
- W2790607534 hasLocation W27906075344 @default.
- W2790607534 hasLocation W27906075345 @default.
- W2790607534 hasOpenAccess W2790607534 @default.
- W2790607534 hasPrimaryLocation W27906075341 @default.
- W2790607534 hasRelatedWork W1986197409 @default.
- W2790607534 hasRelatedWork W2092543281 @default.
- W2790607534 hasRelatedWork W2096858457 @default.
- W2790607534 hasRelatedWork W2104215564 @default.
- W2790607534 hasRelatedWork W2168619725 @default.
- W2790607534 hasRelatedWork W2714704196 @default.