FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790632583> ?p ?o ?g. }

• W2790632583 endingPage "24" @default.
• W2790632583 startingPage "24" @default.
• W2790632583 abstract "<ns4:p><ns4:bold>Background:</ns4:bold> While precision medicines targeting genetic mutations and alterations in non-small cell lung cancer (NSCLC) have been available since 2010, their adoption into clinical practice has been slow. Evidence suggests that a number of barriers, such as insufficient clinician knowledge, a need for training of test providers, or a lack of specific clinical guidelines, may slow the implementation of precision in general. However, little attention has been given to the barriers to providing precision medicines in NSCLC. The purpose of this protocol is to outline the design for a qualitative interview study to identify the barriers and facilitators to the provision of precision medicines for NSCLC.</ns4:p><ns4:p> <ns4:bold>Methods: </ns4:bold>This study will use semi-structured interviews with clinicians (n=10), test providers (n=10), and service commissioners (n=10) to identify the perceived barriers and facilitators to providing historical, current, and future precision medicines in NSCLC. Participants will be identified through mailing list advertisements and snowball sampling. Recruitment will continue until data saturation, indicated by no new themes arising from the data. Interviews will be conducted by telephone to facilitate geographical diversity. The qualitative data will be analysed using a framework analysis with themes anticipated to relate to; relevant barriers to providing precision medicines, the impact of different barriers on medicine provision, changes in the ability to provide precision medicines over time, and strategies to facilitate the provision of precision medicines.</ns4:p><ns4:p> <ns4:bold>Ethics: </ns4:bold>This study has been approved by the University of Manchester Proportionate Review Research Ethics Committee (Reference number: 2017-1885-3619). Written consent will be obtained from all participants.</ns4:p><ns4:p> <ns4:bold>Conclusion: </ns4:bold>This study is the first to explore the barriers and facilitators to providing precision medicines for NSCLC in the English NHS. The findings will inform strategies to improve the implementation of future precision medicines. These findings will be disseminated in peer-reviewed publications and national and international conferences.</ns4:p>" @default.
• W2790632583 created "2018-03-29" @default.
• W2790632583 creator A5014086012 @default.
• W2790632583 creator A5046518245 @default.
• W2790632583 creator A5074121579 @default.
• W2790632583 creator A5080744307 @default.
• W2790632583 date "2018-03-08" @default.
• W2790632583 modified "2023-09-27" @default.
• W2790632583 title "Understanding barriers to the introduction of precision medicines in non-small cell lung cancer: A qualitative interview protocol" @default.
• W2790632583 cites W1964598835 @default.
• W2790632583 cites W1976770755 @default.
• W2790632583 cites W1989084966 @default.
• W2790632583 cites W2004758857 @default.
• W2790632583 cites W2004828581 @default.
• W2790632583 cites W2021100097 @default.
• W2790632583 cites W2032263498 @default.
• W2790632583 cites W2032451354 @default.
• W2790632583 cites W2042621864 @default.
• W2790632583 cites W2045324723 @default.
• W2790632583 cites W2068117882 @default.
• W2790632583 cites W2085028749 @default.
• W2790632583 cites W2086972901 @default.
• W2790632583 cites W2109682271 @default.
• W2790632583 cites W2113973202 @default.
• W2790632583 cites W2116322933 @default.
• W2790632583 cites W2754799758 @default.
• W2790632583 cites W2785301912 @default.
• W2790632583 cites W4237095992 @default.
• W2790632583 doi "https://doi.org/10.12688/wellcomeopenres.13976.1" @default.
• W2790632583 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5934686" @default.
• W2790632583 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29780892" @default.
• W2790632583 hasPublicationYear "2018" @default.
• W2790632583 type Work @default.
• W2790632583 sameAs 2790632583 @default.
• W2790632583 citedByCount "9" @default.
• W2790632583 countsByYear W27906325832019 @default.
• W2790632583 countsByYear W27906325832020 @default.
• W2790632583 countsByYear W27906325832021 @default.
• W2790632583 countsByYear W27906325832022 @default.
• W2790632583 crossrefType "journal-article" @default.
• W2790632583 hasAuthorship W2790632583A5014086012 @default.
• W2790632583 hasAuthorship W2790632583A5046518245 @default.
• W2790632583 hasAuthorship W2790632583A5074121579 @default.
• W2790632583 hasAuthorship W2790632583A5080744307 @default.
• W2790632583 hasBestOaLocation W27906325831 @default.
• W2790632583 hasConcept C106399304 @default.
• W2790632583 hasConcept C142724271 @default.
• W2790632583 hasConcept C144024400 @default.
• W2790632583 hasConcept C15744967 @default.
• W2790632583 hasConcept C163763905 @default.
• W2790632583 hasConcept C190248442 @default.
• W2790632583 hasConcept C36289849 @default.
• W2790632583 hasConcept C512399662 @default.
• W2790632583 hasConcept C71924100 @default.
• W2790632583 hasConceptScore W2790632583C106399304 @default.
• W2790632583 hasConceptScore W2790632583C142724271 @default.
• W2790632583 hasConceptScore W2790632583C144024400 @default.
• W2790632583 hasConceptScore W2790632583C15744967 @default.
• W2790632583 hasConceptScore W2790632583C163763905 @default.
• W2790632583 hasConceptScore W2790632583C190248442 @default.
• W2790632583 hasConceptScore W2790632583C36289849 @default.
• W2790632583 hasConceptScore W2790632583C512399662 @default.
• W2790632583 hasConceptScore W2790632583C71924100 @default.
• W2790632583 hasFunder F4320307874 @default.
• W2790632583 hasLocation W27906325831 @default.
• W2790632583 hasLocation W27906325832 @default.
• W2790632583 hasLocation W27906325833 @default.
• W2790632583 hasLocation W27906325834 @default.
• W2790632583 hasOpenAccess W2790632583 @default.
• W2790632583 hasPrimaryLocation W27906325831 @default.
• W2790632583 hasRelatedWork W1677866193 @default.
• W2790632583 hasRelatedWork W2031401537 @default.
• W2790632583 hasRelatedWork W2748952813 @default.
• W2790632583 hasRelatedWork W2899084033 @default.
• W2790632583 hasRelatedWork W2914623945 @default.
• W2790632583 hasRelatedWork W3111956637 @default.
• W2790632583 hasRelatedWork W3199448679 @default.
• W2790632583 hasRelatedWork W4205110644 @default.
• W2790632583 hasRelatedWork W4283651166 @default.
• W2790632583 hasRelatedWork W4290652174 @default.
• W2790632583 hasVolume "3" @default.
• W2790632583 isParatext "false" @default.
• W2790632583 isRetracted "false" @default.
• W2790632583 magId "2790632583" @default.
• W2790632583 workType "article" @default.