Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790644375> ?p ?o ?g. }
- W2790644375 endingPage "241" @default.
- W2790644375 startingPage "233" @default.
- W2790644375 abstract "The administration of follicle-stimulating hormone (FSH) prior to oocyte retrieval improves oocyte developmental competence. During bovine embryo production in vitro, however, oocytes are typically derived from FSH-unprimed animals. In the current study, we examined the effect of pre-in vitro maturation (IVM) with cAMP modulators, also known as the second messengers of FSH, on the developmental competence of oocytes derived from small antral follicles (2–4 mm) of FSH-unprimed animals. Pre-IVM with N6,2ʹ-O-dibutyryladenosine 3′,5′-cyclicmonophosphate (dbcAMP) and 3-isobutyl-1-methylxanthine (IBMX) for 2 h improved the blastocyst formation in oocytes stimulated by FSH or amphiregulin (AREG). Furthermore, pre-IVM enhanced the expression of the FSH- or AREG-stimulated extracellular matrix-related genes HAS2, TNFAIP6, and PTGS2, and epidermal growth factor (EGF)-like peptide-related genes AREG and EREG. Additionally, pre-IVM with dbcAMP and IBMX enhanced the expression of EGFR, and also increased and prolonged cumulus cell-oocyte gap junctional communication. The improved oocyte development observed using the pre-IVM protocol was ablated by an EGF receptor phosphorylation inhibitor. These results indicate that pre-IVM with cAMP modulators could contribute to the acquisition of developmental competence by bovine oocytes from small antral follicles through the modulation of EGF receptor signaling and oocyte-cumulus/cumulus-cumulus gap junctional communication." @default.
- W2790644375 created "2018-03-29" @default.
- W2790644375 creator A5022976988 @default.
- W2790644375 creator A5031797927 @default.
- W2790644375 creator A5035470160 @default.
- W2790644375 creator A5054153588 @default.
- W2790644375 creator A5085476594 @default.
- W2790644375 creator A5085789327 @default.
- W2790644375 date "2018-01-01" @default.
- W2790644375 modified "2023-10-16" @default.
- W2790644375 title "Effect of pre-<i>in vitro</i> maturation with cAMP modulators on the acquisition of oocyte developmental competence in cattle" @default.
- W2790644375 cites W1605757439 @default.
- W2790644375 cites W1805952594 @default.
- W2790644375 cites W1966584094 @default.
- W2790644375 cites W1972509779 @default.
- W2790644375 cites W1977088863 @default.
- W2790644375 cites W1985394131 @default.
- W2790644375 cites W1987945086 @default.
- W2790644375 cites W1990375473 @default.
- W2790644375 cites W1998095360 @default.
- W2790644375 cites W2000039835 @default.
- W2790644375 cites W2001107123 @default.
- W2790644375 cites W2016010155 @default.
- W2790644375 cites W2016570571 @default.
- W2790644375 cites W2017023141 @default.
- W2790644375 cites W2054820071 @default.
- W2790644375 cites W2056555106 @default.
- W2790644375 cites W2058732512 @default.
- W2790644375 cites W2062678765 @default.
- W2790644375 cites W2062926201 @default.
- W2790644375 cites W2079812680 @default.
- W2790644375 cites W2082421790 @default.
- W2790644375 cites W2084172300 @default.
- W2790644375 cites W2085684986 @default.
- W2790644375 cites W2086691923 @default.
- W2790644375 cites W2102560485 @default.
- W2790644375 cites W2106654447 @default.
- W2790644375 cites W2106787268 @default.
- W2790644375 cites W2109121993 @default.
- W2790644375 cites W2112740166 @default.
- W2790644375 cites W2115150268 @default.
- W2790644375 cites W2124321004 @default.
- W2790644375 cites W2124596832 @default.
- W2790644375 cites W2124838379 @default.
- W2790644375 cites W2133586829 @default.
- W2790644375 cites W2137883218 @default.
- W2790644375 cites W2149237119 @default.
- W2790644375 cites W2150019785 @default.
- W2790644375 cites W2153858086 @default.
- W2790644375 cites W2158119378 @default.
- W2790644375 cites W2162917886 @default.
- W2790644375 cites W2163311280 @default.
- W2790644375 cites W2165038710 @default.
- W2790644375 cites W2168920861 @default.
- W2790644375 cites W2169538778 @default.
- W2790644375 cites W2274700016 @default.
- W2790644375 cites W2340936863 @default.
- W2790644375 cites W2461066519 @default.
- W2790644375 cites W2737168299 @default.
- W2790644375 cites W2755027851 @default.
- W2790644375 cites W301851631 @default.
- W2790644375 doi "https://doi.org/10.1262/jrd.2018-009" @default.
- W2790644375 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6021610" @default.
- W2790644375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29503399" @default.
- W2790644375 hasPublicationYear "2018" @default.
- W2790644375 type Work @default.
- W2790644375 sameAs 2790644375 @default.
- W2790644375 citedByCount "29" @default.
- W2790644375 countsByYear W27906443752018 @default.
- W2790644375 countsByYear W27906443752019 @default.
- W2790644375 countsByYear W27906443752020 @default.
- W2790644375 countsByYear W27906443752021 @default.
- W2790644375 countsByYear W27906443752023 @default.
- W2790644375 crossrefType "journal-article" @default.
- W2790644375 hasAuthorship W2790644375A5022976988 @default.
- W2790644375 hasAuthorship W2790644375A5031797927 @default.
- W2790644375 hasAuthorship W2790644375A5035470160 @default.
- W2790644375 hasAuthorship W2790644375A5054153588 @default.
- W2790644375 hasAuthorship W2790644375A5085476594 @default.
- W2790644375 hasAuthorship W2790644375A5085789327 @default.
- W2790644375 hasBestOaLocation W27906443751 @default.
- W2790644375 hasConcept C126322002 @default.
- W2790644375 hasConcept C134018914 @default.
- W2790644375 hasConcept C142773365 @default.
- W2790644375 hasConcept C163949779 @default.
- W2790644375 hasConcept C16685009 @default.
- W2790644375 hasConcept C170493617 @default.
- W2790644375 hasConcept C196843134 @default.
- W2790644375 hasConcept C24998067 @default.
- W2790644375 hasConcept C2775966511 @default.
- W2790644375 hasConcept C2776362946 @default.
- W2790644375 hasConcept C2776690073 @default.
- W2790644375 hasConcept C2778177303 @default.
- W2790644375 hasConcept C2779276759 @default.
- W2790644375 hasConcept C2780806702 @default.
- W2790644375 hasConcept C2781298581 @default.
- W2790644375 hasConcept C54355233 @default.
- W2790644375 hasConcept C71315377 @default.