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• W2790657829 abstract "Reproductive menopause is recognised as a pause of reproductive ability due to the decline of ovarian reserve with age. The time period preceding menopause, called perimenopause, involves a transition period of variations in the menstrual cycle and endocrine levels. While fertility declines with age, perimenopausal conception remains a challenge regarding the chances of pregnancy achievement. Although IVF is widely used in the management of infertility in women of advanced maternal age, the extremely low pregnancy rates achieved in these patients necessitate to consider alternative options with higher success rates. Oocyte donation represents an efficacious and well-established treatment option in ART, particularly in perimenopausal and menopausal women. Higher pregnancy and delivery rates, as well as lower miscarriage rates have been reported with the use of donated oocytes in older women. However, obstetrical and neonatal complications seem to be increased in pregnancies with oocyte donation, raising ethical and social considerations. In order to minimize the risk of serious complications, appropriate management strategies with regard to oocyte donation should be evaluated after careful selection of patients. Moreover, a detailed medical evaluation and a thorough counselling of patients interested in receiving donated oocytes need to be offered." @default.
• W2790657829 created "2018-03-29" @default.
• W2790657829 creator A5012599511 @default.
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• W2790657829 date "2017-07-25" @default.
• W2790657829 modified "2023-09-27" @default.
• W2790657829 title "Oocyte Donation in Perimenopausal and Menopausal Women" @default.
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• W2790657829 doi "https://doi.org/10.1007/978-3-319-63540-8_7" @default.
• W2790657829 hasPublicationYear "2017" @default.
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