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• W2790673148 abstract "Phagocytosis is a complex and elegant mechanism requiring finely coordinated deformation and restructuring of the membrane and the underlying cytoskeleton. Here we discuss the early events of receptor clustering and engagement required for signal transduction and actin remodeling. In addition, we summarize recent studies of the mechanisms whereby the nascent phagosome seals and evolves into a degradative phagolysosome by a process that seemingly involves the autophagic machinery. These studies provided new insights of the molecular basis of this long-appreciated, essential homeostatic process." @default.
• W2790673148 created "2018-03-29" @default.
• W2790673148 creator A5063705444 @default.
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• W2790673148 date "2018-02-01" @default.
• W2790673148 modified "2023-10-14" @default.
• W2790673148 title "How to build a phagosome: new concepts for an old process" @default.
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• W2790673148 doi "https://doi.org/10.1016/j.ceb.2018.01.009" @default.
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