Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790719087> ?p ?o ?g. }
- W2790719087 abstract "Abstract Sexual behavior is essential for the survival of many species. In female rodents, mate preference and copulatory behavior depend on pheromones and are synchronized with ovulation to ensure reproductive success. The neural circuits driving this orchestration in the brain have, however, remained elusive. Here, we demonstrate that neurons controlling ovulation in the mammalian brain are at the core of a branching neural circuit governing both mate preference and copulatory behavior. We show that male odors detected in the vomeronasal organ activate kisspeptin neurons in female mice. Classical kisspeptin/Kiss1R signaling subsequently triggers olfactory-driven mate preference. In contrast, copulatory behavior is elicited by kisspeptin neurons in a parallel circuit independent of Kiss1R involving nitric oxide signaling. Consistent with this, we find that kisspeptin neurons impinge onto nitric oxide-synthesizing neurons in the ventromedial hypothalamus. Our data establish kisspeptin neurons as a central regulatory hub orchestrating sexual behavior in the female mouse brain." @default.
- W2790719087 created "2018-03-29" @default.
- W2790719087 creator A5013417986 @default.
- W2790719087 creator A5014093315 @default.
- W2790719087 creator A5016267024 @default.
- W2790719087 creator A5027634486 @default.
- W2790719087 creator A5031290722 @default.
- W2790719087 creator A5032424858 @default.
- W2790719087 creator A5032704402 @default.
- W2790719087 creator A5033612716 @default.
- W2790719087 creator A5047299121 @default.
- W2790719087 creator A5052685703 @default.
- W2790719087 creator A5068481505 @default.
- W2790719087 creator A5083058332 @default.
- W2790719087 date "2018-01-26" @default.
- W2790719087 modified "2023-10-09" @default.
- W2790719087 title "Female sexual behavior in mice is controlled by kisspeptin neurons" @default.
- W2790719087 cites W1522531331 @default.
- W2790719087 cites W1534773110 @default.
- W2790719087 cites W1889524175 @default.
- W2790719087 cites W1904569017 @default.
- W2790719087 cites W1966871608 @default.
- W2790719087 cites W1970736861 @default.
- W2790719087 cites W1972744301 @default.
- W2790719087 cites W1975310201 @default.
- W2790719087 cites W1976797335 @default.
- W2790719087 cites W1980904078 @default.
- W2790719087 cites W1981064972 @default.
- W2790719087 cites W1982951075 @default.
- W2790719087 cites W1984519610 @default.
- W2790719087 cites W1984623813 @default.
- W2790719087 cites W1986161032 @default.
- W2790719087 cites W1986219019 @default.
- W2790719087 cites W1988983853 @default.
- W2790719087 cites W1992041715 @default.
- W2790719087 cites W1993501520 @default.
- W2790719087 cites W1994775100 @default.
- W2790719087 cites W1999934268 @default.
- W2790719087 cites W2005830536 @default.
- W2790719087 cites W2016329811 @default.
- W2790719087 cites W2019914463 @default.
- W2790719087 cites W2020055321 @default.
- W2790719087 cites W2020131252 @default.
- W2790719087 cites W2029773403 @default.
- W2790719087 cites W2038978204 @default.
- W2790719087 cites W2039254286 @default.
- W2790719087 cites W2040020955 @default.
- W2790719087 cites W2045824181 @default.
- W2790719087 cites W2058435755 @default.
- W2790719087 cites W2065118621 @default.
- W2790719087 cites W2065275835 @default.
- W2790719087 cites W2065295152 @default.
- W2790719087 cites W2065679484 @default.
- W2790719087 cites W2067915084 @default.
- W2790719087 cites W2068426167 @default.
- W2790719087 cites W2069103915 @default.
- W2790719087 cites W2069358402 @default.
- W2790719087 cites W2072867057 @default.
- W2790719087 cites W2073220855 @default.
- W2790719087 cites W2078464297 @default.
- W2790719087 cites W2079672661 @default.
- W2790719087 cites W2087517330 @default.
- W2790719087 cites W2087588672 @default.
- W2790719087 cites W2092526783 @default.
- W2790719087 cites W2094786733 @default.
- W2790719087 cites W2104876547 @default.
- W2790719087 cites W2106366423 @default.
- W2790719087 cites W2127843280 @default.
- W2790719087 cites W2129890422 @default.
- W2790719087 cites W2133265697 @default.
- W2790719087 cites W2137652638 @default.
- W2790719087 cites W2148890902 @default.
- W2790719087 cites W2149561999 @default.
- W2790719087 cites W2150398005 @default.
- W2790719087 cites W2151573530 @default.
- W2790719087 cites W2158795213 @default.
- W2790719087 cites W2167495346 @default.
- W2790719087 cites W2167587281 @default.
- W2790719087 cites W2191903912 @default.
- W2790719087 cites W2244688341 @default.
- W2790719087 cites W2346657728 @default.
- W2790719087 cites W2580063601 @default.
- W2790719087 cites W2620758438 @default.
- W2790719087 cites W3023672242 @default.
- W2790719087 doi "https://doi.org/10.1038/s41467-017-02797-2" @default.
- W2790719087 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5786055" @default.
- W2790719087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29374161" @default.
- W2790719087 hasPublicationYear "2018" @default.
- W2790719087 type Work @default.
- W2790719087 sameAs 2790719087 @default.
- W2790719087 citedByCount "110" @default.
- W2790719087 countsByYear W27907190872018 @default.
- W2790719087 countsByYear W27907190872019 @default.
- W2790719087 countsByYear W27907190872020 @default.
- W2790719087 countsByYear W27907190872021 @default.
- W2790719087 countsByYear W27907190872022 @default.
- W2790719087 countsByYear W27907190872023 @default.
- W2790719087 crossrefType "journal-article" @default.
- W2790719087 hasAuthorship W2790719087A5013417986 @default.
- W2790719087 hasAuthorship W2790719087A5014093315 @default.