FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2790766187> ?p ?o ?g. }

• W2790766187 abstract "The dinitroaniline herbicides (particularly trifluralin) have been globally used in many crops for selective grass weed control. Consequently, trifluralin resistance has been documented in several important crop weed species and has recently reached a level of concern in Australian Lolium rigidum populations. Here, we report novel mutations in the L. rigidum α-tubulin gene which confer resistance to trifluralin and other dinitroaniline herbicides. Nucleotide mutations at the highly conserved codon Arg-243 resulted in amino acid substitutions of Met or Lys. Rice calli transformed with the mutant 243-Met or 243-Lys α-tubulin genes were 4- to 8-fold more resistant to trifluralin and other dinitroaniline herbicides (e.g. ethalfluralin and pendimethalin) compared to calli transformed with the wild type -tubulin gene from L. rigidum. Comprehensive modelling of molecular docking predicts that Arg-243 is close to the trifluralin binding site on the α-tubulin surface and that replacement of Arg-243 by Met/Lys-243 results in a spatial shift of the trifluralin binding domain, reduction of trifluralin-tubulin contacts, and unfavourable interactions. The major effect of these substitutions is a significant rise of free interaction energy between α-tubulin and trifluralin, as well as between trifluralin and its whole molecular environment. These results demonstrate that the Arg-243 residue in α-tubulin is a determinant for trifluralin sensitivity, and the novel Arg-243-Met/Lys mutations may confer trifluralin resistance in L. rigidum." @default.
• W2790766187 created "2018-03-29" @default.
• W2790766187 creator A5016747508 @default.
• W2790766187 creator A5029806909 @default.
• W2790766187 creator A5033534774 @default.
• W2790766187 creator A5057747879 @default.
• W2790766187 creator A5082707626 @default.
• W2790766187 creator A5088011913 @default.
• W2790766187 date "2018-02-06" @default.
• W2790766187 modified "2023-10-18" @default.
• W2790766187 title "Novel α-Tubulin Mutations Conferring Resistance to Dinitroaniline Herbicides in Lolium rigidum" @default.
• W2790766187 cites W1031578623 @default.
• W2790766187 cites W1497000319 @default.
• W2790766187 cites W1556742432 @default.
• W2790766187 cites W1607931568 @default.
• W2790766187 cites W1681126520 @default.
• W2790766187 cites W1974338131 @default.
• W2790766187 cites W1974488696 @default.
• W2790766187 cites W1982485940 @default.
• W2790766187 cites W2014544223 @default.
• W2790766187 cites W2037311314 @default.
• W2790766187 cites W2040154749 @default.
• W2790766187 cites W2041158925 @default.
• W2790766187 cites W2041791898 @default.
• W2790766187 cites W2044172327 @default.
• W2790766187 cites W2050333027 @default.
• W2790766187 cites W2057477511 @default.
• W2790766187 cites W2057652820 @default.
• W2790766187 cites W2058094979 @default.
• W2790766187 cites W2061652407 @default.
• W2790766187 cites W2067174909 @default.
• W2790766187 cites W2072830954 @default.
• W2790766187 cites W2075499553 @default.
• W2790766187 cites W2077157740 @default.
• W2790766187 cites W2084882191 @default.
• W2790766187 cites W2087277033 @default.
• W2790766187 cites W2087596773 @default.
• W2790766187 cites W2093854934 @default.
• W2790766187 cites W2094426091 @default.
• W2790766187 cites W2095145098 @default.
• W2790766187 cites W2106645410 @default.
• W2790766187 cites W2122741144 @default.
• W2790766187 cites W2122925027 @default.
• W2790766187 cites W2129575581 @default.
• W2790766187 cites W2131961997 @default.
• W2790766187 cites W2143224578 @default.
• W2790766187 cites W2144786472 @default.
• W2790766187 cites W2151013142 @default.
• W2790766187 cites W2151183956 @default.
• W2790766187 cites W2160121979 @default.
• W2790766187 cites W2162785195 @default.
• W2790766187 cites W2163389258 @default.
• W2790766187 cites W218583583 @default.
• W2790766187 cites W273713157 @default.
• W2790766187 cites W2765649121 @default.
• W2790766187 cites W2770145820 @default.
• W2790766187 cites W4318373886 @default.
• W2790766187 doi "https://doi.org/10.3389/fpls.2018.00097" @default.
• W2790766187 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5810296" @default.
• W2790766187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29472938" @default.
• W2790766187 hasPublicationYear "2018" @default.
• W2790766187 type Work @default.
• W2790766187 sameAs 2790766187 @default.
• W2790766187 citedByCount "42" @default.
• W2790766187 countsByYear W27907661872018 @default.
• W2790766187 countsByYear W27907661872019 @default.
• W2790766187 countsByYear W27907661872020 @default.
• W2790766187 countsByYear W27907661872021 @default.
• W2790766187 countsByYear W27907661872022 @default.
• W2790766187 countsByYear W27907661872023 @default.
• W2790766187 crossrefType "journal-article" @default.
• W2790766187 hasAuthorship W2790766187A5016747508 @default.
• W2790766187 hasAuthorship W2790766187A5029806909 @default.
• W2790766187 hasAuthorship W2790766187A5033534774 @default.
• W2790766187 hasAuthorship W2790766187A5057747879 @default.
• W2790766187 hasAuthorship W2790766187A5082707626 @default.
• W2790766187 hasAuthorship W2790766187A5088011913 @default.
• W2790766187 hasBestOaLocation W27907661871 @default.
• W2790766187 hasConcept C104317684 @default.
• W2790766187 hasConcept C143065580 @default.
• W2790766187 hasConcept C147273371 @default.
• W2790766187 hasConcept C20418707 @default.
• W2790766187 hasConcept C2775891814 @default.
• W2790766187 hasConcept C2776425178 @default.
• W2790766187 hasConcept C2778302866 @default.
• W2790766187 hasConcept C2779294082 @default.
• W2790766187 hasConcept C2908854999 @default.
• W2790766187 hasConcept C54355233 @default.
• W2790766187 hasConcept C55493867 @default.
• W2790766187 hasConcept C59822182 @default.
• W2790766187 hasConcept C6557445 @default.
• W2790766187 hasConcept C84425145 @default.
• W2790766187 hasConcept C86803240 @default.
• W2790766187 hasConceptScore W2790766187C104317684 @default.
• W2790766187 hasConceptScore W2790766187C143065580 @default.
• W2790766187 hasConceptScore W2790766187C147273371 @default.
• W2790766187 hasConceptScore W2790766187C20418707 @default.
• W2790766187 hasConceptScore W2790766187C2775891814 @default.
• W2790766187 hasConceptScore W2790766187C2776425178 @default.
• W2790766187 hasConceptScore W2790766187C2778302866 @default.

• next