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• W2791024098 abstract "The blacklegged tick, Ixodes scapularis, is the primary vector to humans in the eastern United States of the deer tick virus lineage of Powassan virus (Powassan virus disease); the protozoan parasite Babesia microti (babesiosis); and multiple bacterial disease agents including Anaplasma phagocytophilum (anaplasmosis), Borrelia burgdorferi and Borrelia mayonii (Lyme disease), Borrelia miyamotoi (relapsing fever-like illness, named Borrelia miyamotoi disease), and Ehrlichia muris eauclairensis (a minor causative agent of ehrlichiosis). With the notable exception of Powassan virus, which can be transmitted within minutes after attachment by an infected tick, there is no doubt that the risk of transmission of other I. scapularis-borne pathogens, including Lyme disease spirochetes, increases with the length of time (number of days) infected ticks are allowed to remain attached. This review summarizes data from experimental transmission studies to reinforce the important disease-prevention message that regular (at least daily) tick checks and prompt tick removal has strong potential to reduce the risk of transmission of I. scapularis-borne bacterial and parasitic pathogens from infected attached ticks. The most likely scenario for human exposure to an I. scapularis-borne pathogen is the bite by a single infected tick. However, recent reviews have failed to make a clear distinction between data based on transmission studies where experimental hosts were fed upon by a single versus multiple infected ticks. A summary of data from experimental studies on transmission of Lyme disease spirochetes (Bo. burgdorferi and Bo. mayonii) by I. scapularis nymphs indicates that the probability of transmission resulting in host infection, at time points from 24 to 72 h after nymphal attachment, is higher when multiple infected ticks feed together as compared to feeding by a single infected tick. In the specific context of risk for human infection, the most relevant experimental studies therefore are those where the probability of pathogen transmission at a given point in time after attachment was determined using a single infected tick. The minimum duration of attachment by single infected I. scapularis nymphs required for transmission to result in host infection is poorly defined for most pathogens, but experimental studies have shown that Powassan virus can be transmitted within 15 min of tick attachment and both A. phagocytophilum and Bo. miyamotoi within the first 24 h of attachment. There is no experimental evidence for transmission of Lyme disease spirochetes by single infected I. scapularis nymphs to result in host infection when ticks are attached for only 24 h (despite exposure of nearly 90 experimental rodent hosts across multiple studies) but the probability of transmission resulting in host infection appears to increase to approximately 10% by 48 h and reach 70% by 72 h for Bo. burgdorferi. Caveats to the results from experimental transmission studies, including specific circumstances (such as re-attachment of previously partially fed infected ticks) that may lead to more rapid transmission are discussed." @default.
• W2791024098 created "2018-03-29" @default.
• W2791024098 creator A5017634712 @default.
• W2791024098 date "2018-03-01" @default.
• W2791024098 modified "2023-10-14" @default.
• W2791024098 title "Pathogen transmission in relation to duration of attachment by Ixodes scapularis ticks" @default.
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• W2791024098 cites W1603513280 @default.
• W2791024098 cites W1613362490 @default.
• W2791024098 cites W1673989603 @default.
• W2791024098 cites W1905802871 @default.
• W2791024098 cites W1965534755 @default.
• W2791024098 cites W1969796579 @default.
• W2791024098 cites W1972226795 @default.
• W2791024098 cites W1983166091 @default.
• W2791024098 cites W1984353964 @default.
• W2791024098 cites W2001549526 @default.
• W2791024098 cites W2002800432 @default.
• W2791024098 cites W2010752624 @default.
• W2791024098 cites W2013636685 @default.
• W2791024098 cites W2019962465 @default.
• W2791024098 cites W2033077259 @default.
• W2791024098 cites W2038533214 @default.
• W2791024098 cites W2047283050 @default.
• W2791024098 cites W2048177423 @default.
• W2791024098 cites W2052325912 @default.
• W2791024098 cites W2067799111 @default.
• W2791024098 cites W2077162746 @default.
• W2791024098 cites W2083417553 @default.
• W2791024098 cites W2087073242 @default.
• W2791024098 cites W2092413898 @default.
• W2791024098 cites W2093757815 @default.
• W2791024098 cites W2094428815 @default.
• W2791024098 cites W2101971468 @default.
• W2791024098 cites W2103355691 @default.
• W2791024098 cites W2107400788 @default.
• W2791024098 cites W2112648191 @default.
• W2791024098 cites W2121336243 @default.
• W2791024098 cites W2121386707 @default.
• W2791024098 cites W2126816729 @default.
• W2791024098 cites W2127138573 @default.
• W2791024098 cites W2129506675 @default.
• W2791024098 cites W2131114958 @default.
• W2791024098 cites W2133246541 @default.
• W2791024098 cites W2134612626 @default.
• W2791024098 cites W2140356656 @default.
• W2791024098 cites W2146707036 @default.
• W2791024098 cites W2148397022 @default.
• W2791024098 cites W2157775556 @default.
• W2791024098 cites W2159511723 @default.
• W2791024098 cites W2160801106 @default.
• W2791024098 cites W2160953240 @default.
• W2791024098 cites W2163754922 @default.
• W2791024098 cites W2167931313 @default.
• W2791024098 cites W2168950809 @default.
• W2791024098 cites W2169447404 @default.
• W2791024098 cites W2174402847 @default.
• W2791024098 cites W2178861536 @default.
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• W2791024098 cites W2264549060 @default.
• W2791024098 cites W2265417168 @default.
• W2791024098 cites W2312934348 @default.
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• W2791024098 cites W2736625367 @default.
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• W2791024098 doi "https://doi.org/10.1016/j.ttbdis.2018.01.002" @default.
• W2791024098 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5857464" @default.
• W2791024098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29398603" @default.
• W2791024098 hasPublicationYear "2018" @default.
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