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- W2791034227 abstract "Primary liver cancer is a common kind of digestive cancers with high malignancy, causing 745,500 deaths each year. Hepatocellular carcinoma is the major pathological type of primary liver cancer. Traditional treatment methods for patients with hepatocellular carcinoma have shown poor efficacy in killing residual cancer cells for a long time. In recent years, tumor immunotherapy has emerged as a promising method owing to its safety and efficacy with respect to delaying the progression of advanced tumors and protecting postoperative patients against tumor relapse and metastasis. Immune tolerance and suppression in tumor microenvironments are the theoretical basis of immunotherapy. Adoptive cell therapy functions by stimulating and cultivating autologous lymphocytes ex vivo and then reinfusing them into the patient to kill cancer cells. Cancer vaccination is performed using antigenic substances to activate tumor-specific immune responses. Immune checkpoint inhibitors can reactivate tumor-specific T cells and develop an antitumor effect by suppressing checkpoint-mediated signaling. Oncolytic viruses may selectively replicate in tumor cells and cause lysis without harming normal tissues. Here, we briefly introduce the mechanism of immunosuppression in hepatocellular carcinoma and summarize the rationale of the four major immunotherapeutic approaches with their current advances." @default.
- W2791034227 created "2018-03-29" @default.
- W2791034227 creator A5002343596 @default.
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- W2791034227 creator A5081442383 @default.
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- W2791034227 date "2018-01-01" @default.
- W2791034227 modified "2023-10-18" @default.
- W2791034227 title "Immunotherapy for Hepatocellular Carcinoma: Current Advances and Future Expectations" @default.
- W2791034227 cites W138028528 @default.
- W2791034227 cites W1574421689 @default.
- W2791034227 cites W1604141497 @default.
- W2791034227 cites W1719275795 @default.
- W2791034227 cites W1867445539 @default.
- W2791034227 cites W1882940783 @default.
- W2791034227 cites W1913328895 @default.
- W2791034227 cites W1920564500 @default.
- W2791034227 cites W1966259152 @default.
- W2791034227 cites W1980638418 @default.
- W2791034227 cites W1985310011 @default.
- W2791034227 cites W1987468883 @default.
- W2791034227 cites W1988464279 @default.
- W2791034227 cites W1988637965 @default.
- W2791034227 cites W1992450231 @default.
- W2791034227 cites W1993971516 @default.
- W2791034227 cites W1994594038 @default.
- W2791034227 cites W2002132740 @default.
- W2791034227 cites W2005335309 @default.
- W2791034227 cites W2005484337 @default.
- W2791034227 cites W2008182044 @default.
- W2791034227 cites W2013229350 @default.
- W2791034227 cites W2018786027 @default.
- W2791034227 cites W2026092903 @default.
- W2791034227 cites W2037882261 @default.
- W2791034227 cites W2038739157 @default.
- W2791034227 cites W2052730188 @default.
- W2791034227 cites W2054090124 @default.
- W2791034227 cites W2063264144 @default.
- W2791034227 cites W2078805591 @default.
- W2791034227 cites W2078844752 @default.
- W2791034227 cites W2081493969 @default.
- W2791034227 cites W2084510043 @default.
- W2791034227 cites W2087294934 @default.
- W2791034227 cites W2088919112 @default.
- W2791034227 cites W2093527529 @default.
- W2791034227 cites W2097849707 @default.
- W2791034227 cites W2098005365 @default.
- W2791034227 cites W2102754583 @default.
- W2791034227 cites W2108883303 @default.
- W2791034227 cites W2117614828 @default.
- W2791034227 cites W2126908586 @default.
- W2791034227 cites W2136683850 @default.
- W2791034227 cites W2137871019 @default.
- W2791034227 cites W214287619 @default.
- W2791034227 cites W2148334703 @default.
- W2791034227 cites W2150544967 @default.
- W2791034227 cites W2153267053 @default.
- W2791034227 cites W2156555632 @default.
- W2791034227 cites W2160874621 @default.
- W2791034227 cites W2168091280 @default.
- W2791034227 cites W2169579205 @default.
- W2791034227 cites W2177293270 @default.
- W2791034227 cites W2187430385 @default.
- W2791034227 cites W2209812019 @default.
- W2791034227 cites W2219230917 @default.
- W2791034227 cites W2286120012 @default.
- W2791034227 cites W2301551739 @default.
- W2791034227 cites W2340435799 @default.
- W2791034227 cites W2370428652 @default.
- W2791034227 cites W2398502676 @default.
- W2791034227 cites W2411949725 @default.
- W2791034227 cites W2413809012 @default.
- W2791034227 cites W2415137283 @default.
- W2791034227 cites W2462486272 @default.
- W2791034227 cites W2467765416 @default.
- W2791034227 cites W2469469957 @default.
- W2791034227 cites W2470288072 @default.
- W2791034227 cites W2546700240 @default.
- W2791034227 cites W2562017637 @default.
- W2791034227 cites W2562740476 @default.
- W2791034227 cites W2570177703 @default.
- W2791034227 cites W2591422658 @default.
- W2791034227 cites W2598998146 @default.
- W2791034227 cites W2605532397 @default.
- W2791034227 cites W2606367731 @default.
- W2791034227 cites W2610779387 @default.
- W2791034227 cites W2611096344 @default.
- W2791034227 cites W2616234418 @default.
- W2791034227 cites W2620448000 @default.
- W2791034227 cites W2626421530 @default.
- W2791034227 cites W2726947303 @default.
- W2791034227 cites W2917837889 @default.
- W2791034227 cites W2973685630 @default.
- W2791034227 cites W4233662103 @default.
- W2791034227 cites W638296762 @default.