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- W2791073412 abstract "Colorectal cancer (CRC) metastases accounts for two thirds of death cases. Recently, genetic instability has been recognized as one of the hallmarks of metastatic microenvironment. In this study, we identified the relationship between Rad51, a key factor to perform DNA homologous recombination repair, and CRC metastasis, and further at the first time explored the effect of O-GlcNAc glycosylation of Rad51 protein on CRC cells invasion. Generally, the study indicates a novel posttranslational modification of Rad51 protein may play an important regulatory role in the process of CRC cells invasion and represent a potential therapeutic target for clinical management of CRC patients." @default.
- W2791073412 created "2018-03-29" @default.
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- W2791073412 date "2018-01-01" @default.
- W2791073412 modified "2023-09-30" @default.
- W2791073412 title "O-Glcnac Glycosylation of Rad51 Plays an Important Role in Promoting Colorectal Cancer Cell Invasion" @default.
- W2791073412 doi "https://doi.org/10.4172/2167-7956.1000160" @default.
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