FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2791381939> ?p ?o ?g. }

• W2791381939 endingPage "2367" @default.
• W2791381939 startingPage "2357" @default.
• W2791381939 abstract "Abstract This study purposed to explore the correlation between miR‐129‐5p and TGIF2 and their impacts on glioma cell progression. Differentially expressed miRNA was screened through microarray analysis. MiR‐129‐5p expression levels in glioma tissues and cells were measured by qRT‐PCR. CCK‐8 assay, flow cytometer, transwell assay and wound‐healing assay were employed to detect cell proliferation, apoptosis and cycle, invasiveness and migration, respectively. Dual‐luciferase reporting assay was performed to confirm the targeted relationship between miR‐129‐5p and TGIF2. The effects of TGIF2 expression on cell biological functions were also investigated using the indicated methods. Tumour xenograft was applied to explore the impact of miR‐129‐5p on tumorigenesis in vivo. MiR‐129‐5p expression was down‐regulated in both glioma tissues and glioma cells, while TGIF2 expression was aberrantly higher than normal level. Dual‐luciferase reporter assay validated the targeting relation between miR‐129‐5p and TGIF2 . Overexpression of miR‐129‐5p or down‐regulation of TGIF2 inhibited the proliferation, invasion and migration capacity of glioma cells U87 and U251, and meanwhile blocked the cell cycle as well as induced cell apoptosis. MiR‐129‐5p overexpression repressed the tumour development in vivo. MiR‐129‐5p and TGIF2 had opposite biological functions in glioma cells. MiR‐129‐5p could inhibit glioma cell progression by targeting TGIF2 , shining light for the development of target treatment for glioma." @default.
• W2791381939 created "2018-03-29" @default.
• W2791381939 creator A5019565092 @default.
• W2791381939 creator A5027296421 @default.
• W2791381939 creator A5056435936 @default.
• W2791381939 creator A5083007908 @default.
• W2791381939 date "2018-02-12" @default.
• W2791381939 modified "2023-10-18" @default.
• W2791381939 title "MiR‐129‐5p inhibits glioma cell progression in vitro and in vivo by targeting <i>TGIF2</i>" @default.
• W2791381939 cites W1944738757 @default.
• W2791381939 cites W2007892513 @default.
• W2791381939 cites W2026736431 @default.
• W2791381939 cites W2066966066 @default.
• W2791381939 cites W2165744153 @default.
• W2791381939 cites W2188570089 @default.
• W2791381939 cites W2235523093 @default.
• W2791381939 cites W2265820530 @default.
• W2791381939 cites W2284411767 @default.
• W2791381939 cites W2290148078 @default.
• W2791381939 cites W2415326250 @default.
• W2791381939 cites W2488584660 @default.
• W2791381939 cites W2527607277 @default.
• W2791381939 cites W2532788509 @default.
• W2791381939 cites W2533993890 @default.
• W2791381939 cites W2557680530 @default.
• W2791381939 cites W2565022769 @default.
• W2791381939 cites W2568756219 @default.
• W2791381939 cites W2596796081 @default.
• W2791381939 cites W2619013311 @default.
• W2791381939 cites W2626319282 @default.
• W2791381939 cites W2626794881 @default.
• W2791381939 cites W2687798390 @default.
• W2791381939 cites W2734122632 @default.
• W2791381939 cites W2734530324 @default.
• W2791381939 cites W2738603362 @default.
• W2791381939 cites W2755419034 @default.
• W2791381939 cites W2755780364 @default.
• W2791381939 doi "https://doi.org/10.1111/jcmm.13529" @default.
• W2791381939 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5867105" @default.
• W2791381939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29431269" @default.
• W2791381939 hasPublicationYear "2018" @default.
• W2791381939 type Work @default.
• W2791381939 sameAs 2791381939 @default.
• W2791381939 citedByCount "34" @default.
• W2791381939 countsByYear W27913819392018 @default.
• W2791381939 countsByYear W27913819392019 @default.
• W2791381939 countsByYear W27913819392020 @default.
• W2791381939 countsByYear W27913819392021 @default.
• W2791381939 countsByYear W27913819392022 @default.
• W2791381939 countsByYear W27913819392023 @default.
• W2791381939 crossrefType "journal-article" @default.
• W2791381939 hasAuthorship W2791381939A5019565092 @default.
• W2791381939 hasAuthorship W2791381939A5027296421 @default.
• W2791381939 hasAuthorship W2791381939A5056435936 @default.
• W2791381939 hasAuthorship W2791381939A5083007908 @default.
• W2791381939 hasBestOaLocation W27913819391 @default.
• W2791381939 hasConcept C104317684 @default.
• W2791381939 hasConcept C121608353 @default.
• W2791381939 hasConcept C145059251 @default.
• W2791381939 hasConcept C1491633281 @default.
• W2791381939 hasConcept C185592680 @default.
• W2791381939 hasConcept C190283241 @default.
• W2791381939 hasConcept C207001950 @default.
• W2791381939 hasConcept C2778227246 @default.
• W2791381939 hasConcept C29537977 @default.
• W2791381939 hasConcept C502942594 @default.
• W2791381939 hasConcept C54355233 @default.
• W2791381939 hasConcept C55493867 @default.
• W2791381939 hasConcept C555283112 @default.
• W2791381939 hasConcept C62112901 @default.
• W2791381939 hasConcept C86803240 @default.
• W2791381939 hasConcept C95444343 @default.
• W2791381939 hasConceptScore W2791381939C104317684 @default.
• W2791381939 hasConceptScore W2791381939C121608353 @default.
• W2791381939 hasConceptScore W2791381939C145059251 @default.
• W2791381939 hasConceptScore W2791381939C1491633281 @default.
• W2791381939 hasConceptScore W2791381939C185592680 @default.
• W2791381939 hasConceptScore W2791381939C190283241 @default.
• W2791381939 hasConceptScore W2791381939C207001950 @default.
• W2791381939 hasConceptScore W2791381939C2778227246 @default.
• W2791381939 hasConceptScore W2791381939C29537977 @default.
• W2791381939 hasConceptScore W2791381939C502942594 @default.
• W2791381939 hasConceptScore W2791381939C54355233 @default.
• W2791381939 hasConceptScore W2791381939C55493867 @default.
• W2791381939 hasConceptScore W2791381939C555283112 @default.
• W2791381939 hasConceptScore W2791381939C62112901 @default.
• W2791381939 hasConceptScore W2791381939C86803240 @default.
• W2791381939 hasConceptScore W2791381939C95444343 @default.
• W2791381939 hasIssue "4" @default.
• W2791381939 hasLocation W27913819391 @default.
• W2791381939 hasLocation W27913819392 @default.
• W2791381939 hasLocation W27913819393 @default.
• W2791381939 hasLocation W27913819394 @default.
• W2791381939 hasOpenAccess W2791381939 @default.
• W2791381939 hasPrimaryLocation W27913819391 @default.
• W2791381939 hasRelatedWork W1956085363 @default.
• W2791381939 hasRelatedWork W2350294409 @default.
• W2791381939 hasRelatedWork W2350542818 @default.

• next