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- W2791401457 abstract "Compared to two-dimensional (2D) conditions, investigation on gene transfection in three-dimensional (3D) conditions is much less extensive. In this work, lamellar nano-hydroxyapatite (L-HAp) with and without magnetism were used as the vectors and gene transfection in 2D and 3D cell culture was carried out and compared. We found that the transfection efficiency in 3D conditions was much higher than 2D cell culture. Additionally, magnetism enhanced transfection efficiency under both 2D and 3D conditions. The findings presented in this study demonstrated that the magnetic L-HAp could be a promising vector in 3D gene transfection." @default.
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- W2791401457 date "2018-08-01" @default.
- W2791401457 modified "2023-09-23" @default.
- W2791401457 title "Magnetic Lamellar Nano-Hydroxyapatite as a Vector for Gene Transfection in Three-Dimensional Cell Culture" @default.
- W2791401457 doi "https://doi.org/10.1166/jnn.2018.15365" @default.
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