Matches in SemOpenAlex for { <https://semopenalex.org/work/W2791709279> ?p ?o ?g. }
- W2791709279 endingPage "68" @default.
- W2791709279 startingPage "56" @default.
- W2791709279 abstract "Nanocellulose is currently gaining attention due to its unique properties. This attention includes its application as building blocks for developing novel functional materials, plant drug and also in drug delivery systems. However, its safety remains largely untested or less understood. Thus, sulphonated nanocellulose (KSS) was prepared from cellulose (KSC) isolated from Khaya senegalensis seed (KS). KS, KSC and KSS were characterized using Fourier transformed infrared (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TG), particle size distribution (PSD), zeta potential and scanning electron microscopy (SEM). The impact of KSS on selected renal markers of oxidative stress, inflammation and apoptosis in Wistar rats was also investigated. Thus, male rats were randomly assigned to four groups of five animals each and were treated with KSS (0, 50, 75 and 100 mg/kg BW) for 14 days. Thereafter, biomarkers of renal oxidative damage, inflammation and immunohistochemical expressions of iNOS, COX-2, Bcl-2 and p53 were evaluated. The results revealed KSS to have crystallinity of 70.40%, it was monomodal and has a flaky surface with agglomerations. KSS had no effect on markers of kidney function and oxidative damage, although there was a generalized hypernatremia after 14 days of exposure. Lastly, KSS enhanced the antioxidant status and immunohistochemical expressions of iNOS and COX-2 in the kidney of the rats. While the biomedical applications of KSS may appear plausible, our data suggests that it could induce renal toxicity via the combined impacts of electrolyte imbalance and inflammation." @default.
- W2791709279 created "2018-03-29" @default.
- W2791709279 creator A5001554031 @default.
- W2791709279 creator A5019589446 @default.
- W2791709279 creator A5034311497 @default.
- W2791709279 creator A5058227410 @default.
- W2791709279 creator A5086560766 @default.
- W2791709279 date "2018-03-01" @default.
- W2791709279 modified "2023-09-25" @default.
- W2791709279 title "Renal toxicological evaluations of sulphonated nanocellulose from Khaya sengalensis seed in Wistar rats" @default.
- W2791709279 cites W1419322303 @default.
- W2791709279 cites W1506043065 @default.
- W2791709279 cites W1523119366 @default.
- W2791709279 cites W1581414347 @default.
- W2791709279 cites W1584309458 @default.
- W2791709279 cites W1595359136 @default.
- W2791709279 cites W1608567816 @default.
- W2791709279 cites W1919388396 @default.
- W2791709279 cites W1965474648 @default.
- W2791709279 cites W1978207122 @default.
- W2791709279 cites W1981356555 @default.
- W2791709279 cites W1985425748 @default.
- W2791709279 cites W1987739207 @default.
- W2791709279 cites W1995479794 @default.
- W2791709279 cites W2007593446 @default.
- W2791709279 cites W2018311092 @default.
- W2791709279 cites W2020358486 @default.
- W2791709279 cites W2025288650 @default.
- W2791709279 cites W2056435965 @default.
- W2791709279 cites W2060194897 @default.
- W2791709279 cites W2062367658 @default.
- W2791709279 cites W2063483499 @default.
- W2791709279 cites W2064567214 @default.
- W2791709279 cites W2065299601 @default.
- W2791709279 cites W2066238972 @default.
- W2791709279 cites W2070912884 @default.
- W2791709279 cites W2078500536 @default.
- W2791709279 cites W2087814397 @default.
- W2791709279 cites W2120574509 @default.
- W2791709279 cites W2123422742 @default.
- W2791709279 cites W2161936823 @default.
- W2791709279 cites W2166994628 @default.
- W2791709279 cites W2192044694 @default.
- W2791709279 cites W2223161052 @default.
- W2791709279 cites W2293014366 @default.
- W2791709279 cites W2314057000 @default.
- W2791709279 cites W2328243799 @default.
- W2791709279 cites W2339224595 @default.
- W2791709279 cites W2343098641 @default.
- W2791709279 cites W2515140632 @default.
- W2791709279 cites W2606251873 @default.
- W2791709279 cites W2624491653 @default.
- W2791709279 doi "https://doi.org/10.1016/j.cbi.2018.02.015" @default.
- W2791709279 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29458016" @default.
- W2791709279 hasPublicationYear "2018" @default.
- W2791709279 type Work @default.
- W2791709279 sameAs 2791709279 @default.
- W2791709279 citedByCount "24" @default.
- W2791709279 countsByYear W27917092792019 @default.
- W2791709279 countsByYear W27917092792020 @default.
- W2791709279 countsByYear W27917092792021 @default.
- W2791709279 countsByYear W27917092792022 @default.
- W2791709279 countsByYear W27917092792023 @default.
- W2791709279 crossrefType "journal-article" @default.
- W2791709279 hasAuthorship W2791709279A5001554031 @default.
- W2791709279 hasAuthorship W2791709279A5019589446 @default.
- W2791709279 hasAuthorship W2791709279A5034311497 @default.
- W2791709279 hasAuthorship W2791709279A5058227410 @default.
- W2791709279 hasAuthorship W2791709279A5086560766 @default.
- W2791709279 hasConcept C126322002 @default.
- W2791709279 hasConcept C178790620 @default.
- W2791709279 hasConcept C185592680 @default.
- W2791709279 hasConcept C2776151105 @default.
- W2791709279 hasConcept C2776914184 @default.
- W2791709279 hasConcept C2777968448 @default.
- W2791709279 hasConcept C2778004101 @default.
- W2791709279 hasConcept C2779251873 @default.
- W2791709279 hasConcept C2780091579 @default.
- W2791709279 hasConcept C55493867 @default.
- W2791709279 hasConcept C60100273 @default.
- W2791709279 hasConcept C71924100 @default.
- W2791709279 hasConcept C98274493 @default.
- W2791709279 hasConceptScore W2791709279C126322002 @default.
- W2791709279 hasConceptScore W2791709279C178790620 @default.
- W2791709279 hasConceptScore W2791709279C185592680 @default.
- W2791709279 hasConceptScore W2791709279C2776151105 @default.
- W2791709279 hasConceptScore W2791709279C2776914184 @default.
- W2791709279 hasConceptScore W2791709279C2777968448 @default.
- W2791709279 hasConceptScore W2791709279C2778004101 @default.
- W2791709279 hasConceptScore W2791709279C2779251873 @default.
- W2791709279 hasConceptScore W2791709279C2780091579 @default.
- W2791709279 hasConceptScore W2791709279C55493867 @default.
- W2791709279 hasConceptScore W2791709279C60100273 @default.
- W2791709279 hasConceptScore W2791709279C71924100 @default.
- W2791709279 hasConceptScore W2791709279C98274493 @default.
- W2791709279 hasLocation W27917092791 @default.
- W2791709279 hasLocation W27917092792 @default.
- W2791709279 hasOpenAccess W2791709279 @default.