Matches in SemOpenAlex for { <https://semopenalex.org/work/W2791948288> ?p ?o ?g. }
- W2791948288 endingPage "268" @default.
- W2791948288 startingPage "261" @default.
- W2791948288 abstract "As one specialized subset of regulatory T cells (Tregs), follicular regulatory T cells (TFR) could suppress follicular helper T cells (TFH) and B cells in germinal centers to maintain immune homeostasis. The unbalance of TFR and TFH cells could result in abnormal germinal center responses and contribute to pathogenesis of autoimmune diseases. However, the role of TFR cells in systemic lupus erythematosus (SLE) remains unclear. This study revealed a significant increase of CD4+CXCR5+FOXP3+ TFR cells in peripheral blood of SLE patients compared with healthy controls. Meanwhile, the suppression ability of circulating TFR cells was not altered. The ratios of TFR/TFH were increased in SLE patients and the frequency of TFR was positively correlated with auto-antibodies and SLEDAI scores of SLE patients. Our results demonstrated that circulating TFR cells were increased during SLE, which suggested that elevated TFR might be a response to the pathogenesis of SLE to suppress TFH function and may provide novel insight for the pathogenesis of SLE." @default.
- W2791948288 created "2018-03-29" @default.
- W2791948288 creator A5010470652 @default.
- W2791948288 creator A5018662629 @default.
- W2791948288 creator A5060213367 @default.
- W2791948288 creator A5066602508 @default.
- W2791948288 creator A5079227909 @default.
- W2791948288 creator A5090366405 @default.
- W2791948288 date "2018-03-01" @default.
- W2791948288 modified "2023-09-27" @default.
- W2791948288 title "Increased circulating CD4+CXCR5+FoxP3+ follicular regulatory T cells correlated with severity of systemic lupus erythematosus patients" @default.
- W2791948288 cites W1518295571 @default.
- W2791948288 cites W1526676414 @default.
- W2791948288 cites W1970480652 @default.
- W2791948288 cites W1984212651 @default.
- W2791948288 cites W1985533946 @default.
- W2791948288 cites W1985613212 @default.
- W2791948288 cites W1997999340 @default.
- W2791948288 cites W1998403286 @default.
- W2791948288 cites W2011470349 @default.
- W2791948288 cites W2015926152 @default.
- W2791948288 cites W2021810330 @default.
- W2791948288 cites W2050509789 @default.
- W2791948288 cites W2055712900 @default.
- W2791948288 cites W2060637301 @default.
- W2791948288 cites W2063223775 @default.
- W2791948288 cites W2064999867 @default.
- W2791948288 cites W2078610240 @default.
- W2791948288 cites W2083959345 @default.
- W2791948288 cites W2085328891 @default.
- W2791948288 cites W2089810611 @default.
- W2791948288 cites W2099495167 @default.
- W2791948288 cites W2099739487 @default.
- W2791948288 cites W2109963496 @default.
- W2791948288 cites W2113687173 @default.
- W2791948288 cites W2129302556 @default.
- W2791948288 cites W2135135005 @default.
- W2791948288 cites W2137446997 @default.
- W2791948288 cites W2140120401 @default.
- W2791948288 cites W2146203649 @default.
- W2791948288 cites W2149076437 @default.
- W2791948288 cites W2166819611 @default.
- W2791948288 cites W2546648712 @default.
- W2791948288 cites W2549287304 @default.
- W2791948288 cites W2591427458 @default.
- W2791948288 doi "https://doi.org/10.1016/j.intimp.2018.01.038" @default.
- W2791948288 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29414660" @default.
- W2791948288 hasPublicationYear "2018" @default.
- W2791948288 type Work @default.
- W2791948288 sameAs 2791948288 @default.
- W2791948288 citedByCount "61" @default.
- W2791948288 countsByYear W27919482882018 @default.
- W2791948288 countsByYear W27919482882019 @default.
- W2791948288 countsByYear W27919482882020 @default.
- W2791948288 countsByYear W27919482882021 @default.
- W2791948288 countsByYear W27919482882022 @default.
- W2791948288 countsByYear W27919482882023 @default.
- W2791948288 crossrefType "journal-article" @default.
- W2791948288 hasAuthorship W2791948288A5010470652 @default.
- W2791948288 hasAuthorship W2791948288A5018662629 @default.
- W2791948288 hasAuthorship W2791948288A5060213367 @default.
- W2791948288 hasAuthorship W2791948288A5066602508 @default.
- W2791948288 hasAuthorship W2791948288A5079227909 @default.
- W2791948288 hasAuthorship W2791948288A5090366405 @default.
- W2791948288 hasConcept C126322002 @default.
- W2791948288 hasConcept C159654299 @default.
- W2791948288 hasConcept C187785154 @default.
- W2791948288 hasConcept C203014093 @default.
- W2791948288 hasConcept C2776708503 @default.
- W2791948288 hasConcept C2778453870 @default.
- W2791948288 hasConcept C2779727006 @default.
- W2791948288 hasConcept C2780942790 @default.
- W2791948288 hasConcept C71924100 @default.
- W2791948288 hasConcept C8891405 @default.
- W2791948288 hasConcept C96926380 @default.
- W2791948288 hasConceptScore W2791948288C126322002 @default.
- W2791948288 hasConceptScore W2791948288C159654299 @default.
- W2791948288 hasConceptScore W2791948288C187785154 @default.
- W2791948288 hasConceptScore W2791948288C203014093 @default.
- W2791948288 hasConceptScore W2791948288C2776708503 @default.
- W2791948288 hasConceptScore W2791948288C2778453870 @default.
- W2791948288 hasConceptScore W2791948288C2779727006 @default.
- W2791948288 hasConceptScore W2791948288C2780942790 @default.
- W2791948288 hasConceptScore W2791948288C71924100 @default.
- W2791948288 hasConceptScore W2791948288C8891405 @default.
- W2791948288 hasConceptScore W2791948288C96926380 @default.
- W2791948288 hasFunder F4320321001 @default.
- W2791948288 hasFunder F4320322919 @default.
- W2791948288 hasLocation W27919482881 @default.
- W2791948288 hasLocation W27919482882 @default.
- W2791948288 hasOpenAccess W2791948288 @default.
- W2791948288 hasPrimaryLocation W27919482881 @default.
- W2791948288 hasRelatedWork W2503016758 @default.
- W2791948288 hasRelatedWork W2531815807 @default.
- W2791948288 hasRelatedWork W2791948288 @default.
- W2791948288 hasRelatedWork W2910439966 @default.
- W2791948288 hasRelatedWork W2946495128 @default.
- W2791948288 hasRelatedWork W3104780139 @default.