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- W2791952337 abstract "Encephaloclastic lesions of the second and third trimesters disrupt normal development and are to be distinguished from primary malformations, which result from an intrinsically abnormal developmental process. When these lesions are suspected, possible antecedents should be sought in the clinical history. Ultrasound and magnetic resonance imaging are the most useful investigations, and are regularly employed for intrauterine evaluation. Differential diagnosis of hydranencephaly includes severe obstructive hydrocephalus and Fowler's familial hydranencephaly syndrome, which, although indistinguishable macroscopically and ultrasonographically, is easily recognizable postmortem, given the pathognomonic glomerular vasculopathy present throughout the central nervous system. Twinning is a well-recognized antecedent for the encephaloclastic lesions, together with maternal poisoning, attempted suicide, attempted abortion and anaphylactic shock. Anti-epileptic measures and physical therapy are the mainstays of treatment. Increasing hydrocephalus may require surgical shunting." @default.
- W2791952337 created "2018-03-29" @default.
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- W2791952337 date "2018-03-09" @default.
- W2791952337 modified "2023-10-16" @default.
- W2791952337 title "Antenatal Disruptive Lesions" @default.
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- W2791952337 doi "https://doi.org/10.1002/9781119013112.ch19" @default.
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