Matches in SemOpenAlex for { <https://semopenalex.org/work/W2792023488> ?p ?o ?g. }
- W2792023488 endingPage "695" @default.
- W2792023488 startingPage "695" @default.
- W2792023488 abstract "Mango “Ataulfo” peel is a rich source of polyphenols (PP), with antioxidant and anti-cancer properties; however, it is unknown whether such antiproliferative activity is related to PP’s antioxidant activity. The content (HPLC-DAD), antioxidant (DPPH, FRAP, ORAC), and antiproliferative activities (MTT) of free (FP) and chemically-released PP from mango ‘Ataulfo’ peel after alkaline (AKP) and acid (AP) hydrolysis, were evaluated. AKP fraction was higher (µg/g DW) in gallic acid (GA; 23,816 ± 284) than AP (5610 ± 8) of FR (not detected) fractions. AKP fraction and GA showed the highest antioxidant activity (DPPH/FRAP/ORAC) and GA’s antioxidant activity follows a single electron transfer (SET) mechanism. AKP and GA also showed the best antiproliferative activity against human colon adenocarcinoma cells (LS180; IC50 (µg/mL) 138.2 ± 2.5 and 45.7 ± 5.2) and mouse connective cells (L929; 93.5 ± 7.7 and 65.3 ± 1.2); Cheminformatics confirmed the hydrophilic nature (LogP, 0.6) and a good absorption capacity (75%) for GA. Data suggests that GA’s antiproliferative activity appears to be related to its antioxidant mechanism, although other mechanisms after its absorption could also be involved." @default.
- W2792023488 created "2018-03-29" @default.
- W2792023488 creator A5007084625 @default.
- W2792023488 creator A5024365425 @default.
- W2792023488 creator A5038306989 @default.
- W2792023488 creator A5039585398 @default.
- W2792023488 creator A5056395034 @default.
- W2792023488 creator A5064421862 @default.
- W2792023488 creator A5070255661 @default.
- W2792023488 date "2018-03-19" @default.
- W2792023488 modified "2023-10-16" @default.
- W2792023488 title "Gallic Acid Content and an Antioxidant Mechanism Are Responsible for the Antiproliferative Activity of ‘Ataulfo’ Mango Peel on LS180 Cells" @default.
- W2792023488 cites W1025135529 @default.
- W2792023488 cites W1540267894 @default.
- W2792023488 cites W1571622960 @default.
- W2792023488 cites W1575881208 @default.
- W2792023488 cites W1683327947 @default.
- W2792023488 cites W1792017131 @default.
- W2792023488 cites W1898647580 @default.
- W2792023488 cites W1965175859 @default.
- W2792023488 cites W1971813656 @default.
- W2792023488 cites W1976080807 @default.
- W2792023488 cites W1979176410 @default.
- W2792023488 cites W1980147235 @default.
- W2792023488 cites W1988519569 @default.
- W2792023488 cites W1997597510 @default.
- W2792023488 cites W2007867745 @default.
- W2792023488 cites W2008509962 @default.
- W2792023488 cites W2012897190 @default.
- W2792023488 cites W2020565622 @default.
- W2792023488 cites W2027966927 @default.
- W2792023488 cites W2031986590 @default.
- W2792023488 cites W2036570895 @default.
- W2792023488 cites W2038115154 @default.
- W2792023488 cites W2040379693 @default.
- W2792023488 cites W2060268121 @default.
- W2792023488 cites W2065399368 @default.
- W2792023488 cites W2065853716 @default.
- W2792023488 cites W2073280600 @default.
- W2792023488 cites W2073725745 @default.
- W2792023488 cites W2081303452 @default.
- W2792023488 cites W2084341569 @default.
- W2792023488 cites W2093979148 @default.
- W2792023488 cites W2100209194 @default.
- W2792023488 cites W2109281708 @default.
- W2792023488 cites W2113250555 @default.
- W2792023488 cites W2113755059 @default.
- W2792023488 cites W2149259648 @default.
- W2792023488 cites W2157558148 @default.
- W2792023488 cites W2165292984 @default.
- W2792023488 cites W2244136435 @default.
- W2792023488 cites W2258248336 @default.
- W2792023488 cites W2277652328 @default.
- W2792023488 cites W2290939416 @default.
- W2792023488 cites W2314935245 @default.
- W2792023488 cites W2330286596 @default.
- W2792023488 cites W2341842950 @default.
- W2792023488 cites W2413586004 @default.
- W2792023488 cites W2417264979 @default.
- W2792023488 cites W2461939371 @default.
- W2792023488 cites W2461997959 @default.
- W2792023488 cites W2466310017 @default.
- W2792023488 cites W2510413148 @default.
- W2792023488 cites W2512174580 @default.
- W2792023488 cites W2550421475 @default.
- W2792023488 cites W2551371267 @default.
- W2792023488 cites W2565237007 @default.
- W2792023488 cites W2566916892 @default.
- W2792023488 cites W2576201848 @default.
- W2792023488 cites W2612045041 @default.
- W2792023488 cites W2617035720 @default.
- W2792023488 cites W2619698442 @default.
- W2792023488 cites W2734859171 @default.
- W2792023488 cites W2779380598 @default.
- W2792023488 cites W2789232275 @default.
- W2792023488 cites W4242780818 @default.
- W2792023488 cites W560377117 @default.
- W2792023488 cites W2207779335 @default.
- W2792023488 doi "https://doi.org/10.3390/molecules23030695" @default.
- W2792023488 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6017175" @default.
- W2792023488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29562699" @default.
- W2792023488 hasPublicationYear "2018" @default.
- W2792023488 type Work @default.
- W2792023488 sameAs 2792023488 @default.
- W2792023488 citedByCount "85" @default.
- W2792023488 countsByYear W27920234882018 @default.
- W2792023488 countsByYear W27920234882019 @default.
- W2792023488 countsByYear W27920234882020 @default.
- W2792023488 countsByYear W27920234882021 @default.
- W2792023488 countsByYear W27920234882022 @default.
- W2792023488 countsByYear W27920234882023 @default.
- W2792023488 crossrefType "journal-article" @default.
- W2792023488 hasAuthorship W2792023488A5007084625 @default.
- W2792023488 hasAuthorship W2792023488A5024365425 @default.
- W2792023488 hasAuthorship W2792023488A5038306989 @default.
- W2792023488 hasAuthorship W2792023488A5039585398 @default.
- W2792023488 hasAuthorship W2792023488A5056395034 @default.
- W2792023488 hasAuthorship W2792023488A5064421862 @default.