FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2792148145> ?p ?o ?g. }

• W2792148145 endingPage "6" @default.
• W2792148145 startingPage "1" @default.
• W2792148145 abstract "The application of local anesthetics, usually administered by subcutaneous injection, is common in the course of diagnostic, therapeutic, and cosmetic dermatology procedures. The effective dermal delivery of lidocaine could offer a solution to many adverse effects caused by needle insertion, such as pain, local reactions or toxicity, and additionally, it avoids the disruption of anatomical landmarks. Therefore, novel dermal formulations of local anesthetics are needed to overcome the barrier function of the skin and provide sufficient and prolonged anesthesia. In our study, we aimed to investigate and compare the penetration profiles of four different lidocaine containing formulations (hydrogel, oleogel, lyotropic liquid crystal and nanostructured lipid carrier) by Raman microscopic mapping of the drug. The application of Raman spectroscopy provided information about the spatial distribution of lidocaine in the skin ex vivo. The penetration of lidocaine from lyotropic liquid crystal and nanostructured carrier reached deeper skin layers and a higher amount of the drug was diffused into the skin, compared with hydrogel and oleogel. This study confirmed that nanostructured carriers can improve skin penetration properties of lidocaine and proved the applicability of Raman spectroscopy in the research of dermatological preparations ex vivo as a nondestructive, relatively easy and fast technique." @default.
• W2792148145 created "2018-03-29" @default.
• W2792148145 creator A5015024546 @default.
• W2792148145 creator A5016005864 @default.
• W2792148145 creator A5030519759 @default.
• W2792148145 creator A5040089178 @default.
• W2792148145 creator A5051861289 @default.
• W2792148145 creator A5079524348 @default.
• W2792148145 date "2018-05-01" @default.
• W2792148145 modified "2023-10-16" @default.
• W2792148145 title "Following-up skin penetration of lidocaine from different vehicles by Raman spectroscopic mapping" @default.
• W2792148145 cites W1691096679 @default.
• W2792148145 cites W1983766165 @default.
• W2792148145 cites W1992385346 @default.
• W2792148145 cites W1995001633 @default.
• W2792148145 cites W2002924638 @default.
• W2792148145 cites W2008916894 @default.
• W2792148145 cites W2015862684 @default.
• W2792148145 cites W2033896540 @default.
• W2792148145 cites W2046209986 @default.
• W2792148145 cites W2049335016 @default.
• W2792148145 cites W2060718968 @default.
• W2792148145 cites W2068201250 @default.
• W2792148145 cites W2086302743 @default.
• W2792148145 cites W2092522582 @default.
• W2792148145 cites W2113486600 @default.
• W2792148145 cites W2141162588 @default.
• W2792148145 cites W2143970002 @default.
• W2792148145 cites W2148176374 @default.
• W2792148145 cites W2150629464 @default.
• W2792148145 cites W2257513045 @default.
• W2792148145 cites W2328918441 @default.
• W2792148145 cites W2332702741 @default.
• W2792148145 cites W2559795339 @default.
• W2792148145 cites W2588952947 @default.
• W2792148145 cites W2614959880 @default.
• W2792148145 cites W2744693990 @default.
• W2792148145 doi "https://doi.org/10.1016/j.jpba.2018.02.056" @default.
• W2792148145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29524770" @default.
• W2792148145 hasPublicationYear "2018" @default.
• W2792148145 type Work @default.
• W2792148145 sameAs 2792148145 @default.
• W2792148145 citedByCount "26" @default.
• W2792148145 countsByYear W27921481452019 @default.
• W2792148145 countsByYear W27921481452020 @default.
• W2792148145 countsByYear W27921481452021 @default.
• W2792148145 countsByYear W27921481452022 @default.
• W2792148145 countsByYear W27921481452023 @default.
• W2792148145 crossrefType "journal-article" @default.
• W2792148145 hasAuthorship W2792148145A5015024546 @default.
• W2792148145 hasAuthorship W2792148145A5016005864 @default.
• W2792148145 hasAuthorship W2792148145A5030519759 @default.
• W2792148145 hasAuthorship W2792148145A5040089178 @default.
• W2792148145 hasAuthorship W2792148145A5051861289 @default.
• W2792148145 hasAuthorship W2792148145A5079524348 @default.
• W2792148145 hasConcept C120665830 @default.
• W2792148145 hasConcept C121332964 @default.
• W2792148145 hasConcept C127413603 @default.
• W2792148145 hasConcept C136229726 @default.
• W2792148145 hasConcept C150903083 @default.
• W2792148145 hasConcept C171250308 @default.
• W2792148145 hasConcept C178790620 @default.
• W2792148145 hasConcept C185592680 @default.
• W2792148145 hasConcept C192562407 @default.
• W2792148145 hasConcept C202751555 @default.
• W2792148145 hasConcept C207001950 @default.
• W2792148145 hasConcept C26291073 @default.
• W2792148145 hasConcept C2778994108 @default.
• W2792148145 hasConcept C2779820397 @default.
• W2792148145 hasConcept C2780149897 @default.
• W2792148145 hasConcept C2910703761 @default.
• W2792148145 hasConcept C40003534 @default.
• W2792148145 hasConcept C42219234 @default.
• W2792148145 hasConcept C42475967 @default.
• W2792148145 hasConcept C55493867 @default.
• W2792148145 hasConcept C71924100 @default.
• W2792148145 hasConcept C80107235 @default.
• W2792148145 hasConcept C86803240 @default.
• W2792148145 hasConcept C98274493 @default.
• W2792148145 hasConceptScore W2792148145C120665830 @default.
• W2792148145 hasConceptScore W2792148145C121332964 @default.
• W2792148145 hasConceptScore W2792148145C127413603 @default.
• W2792148145 hasConceptScore W2792148145C136229726 @default.
• W2792148145 hasConceptScore W2792148145C150903083 @default.
• W2792148145 hasConceptScore W2792148145C171250308 @default.
• W2792148145 hasConceptScore W2792148145C178790620 @default.
• W2792148145 hasConceptScore W2792148145C185592680 @default.
• W2792148145 hasConceptScore W2792148145C192562407 @default.
• W2792148145 hasConceptScore W2792148145C202751555 @default.
• W2792148145 hasConceptScore W2792148145C207001950 @default.
• W2792148145 hasConceptScore W2792148145C26291073 @default.
• W2792148145 hasConceptScore W2792148145C2778994108 @default.
• W2792148145 hasConceptScore W2792148145C2779820397 @default.
• W2792148145 hasConceptScore W2792148145C2780149897 @default.
• W2792148145 hasConceptScore W2792148145C2910703761 @default.
• W2792148145 hasConceptScore W2792148145C40003534 @default.
• W2792148145 hasConceptScore W2792148145C42219234 @default.
• W2792148145 hasConceptScore W2792148145C42475967 @default.

• next