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• W2792157639 endingPage "34" @default.
• W2792157639 startingPage "28" @default.
• W2792157639 abstract "Tardive dyskinesia (TD) is a potentially irreversible and often debilitating movement disorder secondary to chronic use of dopamine receptor blocking medications. Genetic factors have been implicated in the etiology of TD. We therefore have reviewed the most promising genes associated with TD, including DRD2, DRD3, VMAT2, HSPG2, HTR2A, HTR2C, and SOD2. In addition, we present evidence supporting a role for these genes from preclinical models of TD. The current understanding of the etiogenesis of TD is discussed in the light of the recent approvals of valbenazine and deutetrabenazine, VMAT2 inhibitors, for treating TD." @default.
• W2792157639 created "2018-03-29" @default.
• W2792157639 creator A5022096029 @default.
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• W2792157639 creator A5069342968 @default.
• W2792157639 creator A5079389435 @default.
• W2792157639 creator A5082315914 @default.
• W2792157639 date "2018-06-01" @default.
• W2792157639 modified "2023-09-25" @default.
• W2792157639 title "Genetics of tardive dyskinesia: Promising leads and ways forward" @default.
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