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• W2792170951 abstract "Abstract The measurement method for the LA wall thickness (WT) using cardiac computed tomography (CT) is observer dependent and cannot provide a rapid and comprehensive visualisation of the global LA WT. We aim to develop a LA wall-mapping application to display the global LA WT on a coplanar plane. The accuracy, intra-observer, and inter-observer reproducibility of the application were validated using digital/physical phantoms, and CT images of eight patients. This application on CT-based LA WT measures were further validated by testing six pig cardiac specimens. To evaluate its accuracy, the expanded maps of the physical phantom and pig LA were generated from the CT images and compared with the expanded map of the digital phantom and LA wall of pig heart. No significant differences ( p > 0.05) were found between physical phantom and digital phantom as well as pig heart specimen and CT images using our application. Moreover, the analysis was based on the LA physical phantom or images of clinical patients; the results consistently demonstrated high intra-observer reproducibility (ICC > 0.9) and inter-observer reproducibility (ICC > 0.8) and showed good correlation between measures of pig heart specimen and CT data ( r = 0.96, p < 0.001). The application can p rocess and analyse the LA architecture for further visualisation and quantification." @default.
• W2792170951 created "2018-03-29" @default.
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• W2792170951 date "2018-03-08" @default.
• W2792170951 modified "2023-10-11" @default.
• W2792170951 title "Left Atrium Wall-mapping Application for Wall Thickness Visualisation" @default.
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• W2792170951 doi "https://doi.org/10.1038/s41598-018-22089-z" @default.
• W2792170951 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5843597" @default.
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