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• W2792174003 abstract "WS9326H (1), a new cyclic peptide, was isolated from a mudflat-derived Streptomyces strain. Based on analysis by 1D/2D NMR, UV spectroscopy, and mass spectrometry, compound 1 was determined to have the gross structure of a cyclic heptapeptide bearing an unprecedented pyrazolone ring connected to a d-arabinitol via an amide bond. The absolute configuration of 1 was established by multistep chemical derivatizations, comprehensive NMR, and LC/MS analyses of the derivatives and quantum mechanics-based computational methods. WS9326H (1) displayed significant antiangiogenesis activity." @default.
• W2792174003 created "2018-03-29" @default.
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• W2792174003 date "2018-03-20" @default.
• W2792174003 modified "2023-10-11" @default.
• W2792174003 title "WS9326H, an Antiangiogenic Pyrazolone-Bearing Peptide from an Intertidal Mudflat Actinomycete" @default.
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• W2792174003 doi "https://doi.org/10.1021/acs.orglett.8b00546" @default.
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