Matches in SemOpenAlex for { <https://semopenalex.org/work/W2792332391> ?p ?o ?g. }
- W2792332391 endingPage "721" @default.
- W2792332391 startingPage "721" @default.
- W2792332391 abstract "Self-nonself discrimination is a common theme for all of the organisms in different evolutionary branches, which is also the most fundamental step for host immune protection. Plenty of pattern recognition receptors (PRRs) with great diversity have been identified from different organisms to recognize various pathogen-associated molecular patterns (PAMPs) in the last two decades, depicting a complicated scene of host-pathogen interaction. However, the detailed mechanism of the complicate PAMPs–PRRs interactions at the contacting interface between pathogens and hosts is still not well understood. All of the cells are coated by glycosylation complex and thick carbohydrates layer. The different polysaccharides in extracellular matrix of pathogen-host are important for nonself recognition of most organisms. Coincidentally, massive expansion of PRRs, majority of which contain recognition domains of Ig, leucine-rich repeat (LRR), C-type lectin (CTL), C1q and scavenger receptor (SR), have been annotated and identified in invertebrates by screening the available genomic sequence. The phylum Mollusca is one of the largest groups in the animal kingdom with abundant biodiversity providing plenty of solutions about pathogen recognition and immune protection, which might offer a suitable model to figure out the common rules of immune recognition mechanism. The present review summarizes the diverse PRRs and common elements of various PAMPs, especially focusing on the structural and functional characteristics of canonical carbohydrate recognition proteins and some novel proteins functioning in molluscan immune defense system, with the objective to provide new ideas about the immune recognition mechanisms." @default.
- W2792332391 created "2018-03-29" @default.
- W2792332391 creator A5002461253 @default.
- W2792332391 creator A5024421837 @default.
- W2792332391 creator A5052700776 @default.
- W2792332391 creator A5088282650 @default.
- W2792332391 date "2018-03-03" @default.
- W2792332391 modified "2023-10-05" @default.
- W2792332391 title "Pathogen-Derived Carbohydrate Recognition in Molluscs Immune Defense" @default.
- W2792332391 cites W1092112813 @default.
- W2792332391 cites W117510794 @default.
- W2792332391 cites W145329232 @default.
- W2792332391 cites W1568036408 @default.
- W2792332391 cites W1894925520 @default.
- W2792332391 cites W1963752992 @default.
- W2792332391 cites W1964849633 @default.
- W2792332391 cites W1969564749 @default.
- W2792332391 cites W1970227553 @default.
- W2792332391 cites W1971116536 @default.
- W2792332391 cites W1973405021 @default.
- W2792332391 cites W1980213997 @default.
- W2792332391 cites W1981014132 @default.
- W2792332391 cites W1984305420 @default.
- W2792332391 cites W1985636788 @default.
- W2792332391 cites W1986593268 @default.
- W2792332391 cites W1987015602 @default.
- W2792332391 cites W1987935045 @default.
- W2792332391 cites W1988089345 @default.
- W2792332391 cites W1992177235 @default.
- W2792332391 cites W1993274900 @default.
- W2792332391 cites W1994169352 @default.
- W2792332391 cites W1996995262 @default.
- W2792332391 cites W1999839839 @default.
- W2792332391 cites W2001141645 @default.
- W2792332391 cites W2004913085 @default.
- W2792332391 cites W2006317687 @default.
- W2792332391 cites W2006805292 @default.
- W2792332391 cites W2010980655 @default.
- W2792332391 cites W2011091011 @default.
- W2792332391 cites W2013379170 @default.
- W2792332391 cites W2015275262 @default.
- W2792332391 cites W2017125750 @default.
- W2792332391 cites W2017811723 @default.
- W2792332391 cites W2018534189 @default.
- W2792332391 cites W2019779457 @default.
- W2792332391 cites W2019956407 @default.
- W2792332391 cites W2020152576 @default.
- W2792332391 cites W2020310632 @default.
- W2792332391 cites W2020438497 @default.
- W2792332391 cites W2021012107 @default.
- W2792332391 cites W2023686229 @default.
- W2792332391 cites W2024551447 @default.
- W2792332391 cites W2025246774 @default.
- W2792332391 cites W2025826473 @default.
- W2792332391 cites W2026130700 @default.
- W2792332391 cites W2029643771 @default.
- W2792332391 cites W2029723989 @default.
- W2792332391 cites W2030387845 @default.
- W2792332391 cites W2031061362 @default.
- W2792332391 cites W2032756908 @default.
- W2792332391 cites W2034366573 @default.
- W2792332391 cites W2037122060 @default.
- W2792332391 cites W2038102070 @default.
- W2792332391 cites W2038113812 @default.
- W2792332391 cites W2038543523 @default.
- W2792332391 cites W2039939016 @default.
- W2792332391 cites W2040314789 @default.
- W2792332391 cites W2041514411 @default.
- W2792332391 cites W2041971745 @default.
- W2792332391 cites W2042590551 @default.
- W2792332391 cites W2042945416 @default.
- W2792332391 cites W2044461647 @default.
- W2792332391 cites W2045797137 @default.
- W2792332391 cites W2045972201 @default.
- W2792332391 cites W2049401652 @default.
- W2792332391 cites W2055659906 @default.
- W2792332391 cites W2056016933 @default.
- W2792332391 cites W2056407079 @default.
- W2792332391 cites W2058373167 @default.
- W2792332391 cites W2060687897 @default.
- W2792332391 cites W2063961335 @default.
- W2792332391 cites W2065537637 @default.
- W2792332391 cites W2067360027 @default.
- W2792332391 cites W2068619092 @default.
- W2792332391 cites W2073523429 @default.
- W2792332391 cites W2074396626 @default.
- W2792332391 cites W2074964253 @default.
- W2792332391 cites W2075543944 @default.
- W2792332391 cites W2076049880 @default.
- W2792332391 cites W2078911790 @default.
- W2792332391 cites W2079968426 @default.
- W2792332391 cites W2090466949 @default.
- W2792332391 cites W2094800484 @default.
- W2792332391 cites W2096045633 @default.
- W2792332391 cites W2101994976 @default.
- W2792332391 cites W2108613782 @default.
- W2792332391 cites W2111825647 @default.
- W2792332391 cites W2114216755 @default.