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• W2792676941 abstract "A series of planar chiral ferrocene cyclopalladated compounds were synthesized and characterized. The absolute configurations of four compounds were determined by single-crystal X-ray analysis. The cytotoxic activities of the synthesized compounds and cisplatin exhibited different inhibition potencies on the viability of human liver, breast, and colon cancer cell lines. The dinuclear compound 7 was 16-fold more potent than cisplatin in hepatoma cells. Compound 7 was also more effective than cisplatin in the inhibition of hepatoma cell metastasis. Flow cytometry analysis and caspase activity assays indicated that compound 7 exerted antiproliferative activity in cancer cells through the induction of caspase-dependent apoptosis." @default.
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• W2792676941 date "2018-03-22" @default.
• W2792676941 modified "2023-10-16" @default.
• W2792676941 title "Planar Chiral Ferrocene Cyclopalladated Derivatives Induce Caspase-Dependent Apoptosis and Antimetastasis in Cancer Cells" @default.
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• W2792676941 doi "https://doi.org/10.1021/acs.organomet.7b00897" @default.
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