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- W2792694550 abstract "Abstract A series of mononuclear cobalt and nickel complexes of the types [M(NCS)2(L1)2], M = Co 1 or Ni 2, [M(NCS)2(L2)2]·nH2O, M = Co (n = 0) 3 or Ni (n = 2) 4 and [M(NCS)2(L3)2], M = Co 5 or Ni 6, where L1 = benzyl 2-(cyclobutanylidene)hydrazinecarboxylate, L2 = benzyl 2-(cyclopentanylidene)hydrazinecarboxylate and L3 = benzyl 2-(cyclohexanylidene)hydrazinecarboxylate, were synthesized by template reactions of the metal nitrates, ammonium thiocyanate and benzyl carbazate (bc) with cyclobutanone (cb), cyclopentanone (cp) or cyclohexanone (ch). These compounds have been characterized by elemental analysis, infrared, electronic absorption and 1H NMR spectroscopies, together with single crystal X-ray diffraction. Crystal structures of the complexes 1, 3–6 showed that the Schiff base ligands coordinate to the metal ions via the azomethine nitrogen and carbonyl oxygen atoms. In each case the two thiocyanate ligands coordinate through their nitrogen atoms resulting in complexes with a six coordinate octahedral geometry. The thermal stability of the complexes was investigated by TG-DTA and all of the compounds (1–6) undergo endothermic followed by exothermic decomposition processes to form the respective metal oxides. The antibacterial activity of the cobalt(II) and nickel(II) complexes was examined against Gram positive and Gram negative bacteria at concentrations between 40 and 80 μg mL−1. The binding interaction of human serum albumin (HSA) with compounds 1–6 was explored by multi-spectroscopic techniques and docking studies revealed the complexes bind to HSA through hydrophobic interactions. The cytotoxic activity of all of the compounds was evaluated against the K-562 (leukemia cell line) by MTT assays and, remarkably, all of the complexes were found to show good activity towards this cancer cell line. DAPI (4′,6-diamidino-2-phenylindole) staining assay further confirmed that complexes induced leukemia cancer cell death by an apoptosis mechanism." @default.
- W2792694550 created "2018-03-29" @default.
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- W2792694550 date "2018-05-01" @default.
- W2792694550 modified "2023-10-16" @default.
- W2792694550 title "Solvent assisted synthesis, structural characterization and biological evaluation of cobalt(II) and nickel(II) complexes of Schiff bases generated from benzyl carbazate and cyclic ketones" @default.
- W2792694550 cites W1630786301 @default.
- W2792694550 cites W1964069758 @default.
- W2792694550 cites W1965301749 @default.
- W2792694550 cites W1969360633 @default.
- W2792694550 cites W1971114420 @default.
- W2792694550 cites W1972050623 @default.
- W2792694550 cites W1973292723 @default.
- W2792694550 cites W1975862247 @default.
- W2792694550 cites W1978833982 @default.
- W2792694550 cites W1979121587 @default.
- W2792694550 cites W1979368277 @default.
- W2792694550 cites W1979685576 @default.
- W2792694550 cites W1984831780 @default.
- W2792694550 cites W1985920079 @default.
- W2792694550 cites W1990170643 @default.
- W2792694550 cites W1997750725 @default.
- W2792694550 cites W1999940564 @default.
- W2792694550 cites W2000587059 @default.
- W2792694550 cites W2010426016 @default.
- W2792694550 cites W2025396495 @default.
- W2792694550 cites W2027935756 @default.
- W2792694550 cites W2028813195 @default.
- W2792694550 cites W2034380860 @default.
- W2792694550 cites W2050748731 @default.
- W2792694550 cites W2052204371 @default.
- W2792694550 cites W2053323498 @default.
- W2792694550 cites W2055909489 @default.
- W2792694550 cites W2056633522 @default.
- W2792694550 cites W2058732331 @default.
- W2792694550 cites W2061832104 @default.
- W2792694550 cites W2062939164 @default.
- W2792694550 cites W2064261289 @default.
- W2792694550 cites W2066814690 @default.
- W2792694550 cites W2067146937 @default.
- W2792694550 cites W2079164800 @default.
- W2792694550 cites W2080182825 @default.
- W2792694550 cites W2086933827 @default.
- W2792694550 cites W2090776165 @default.
- W2792694550 cites W2091746210 @default.
- W2792694550 cites W2092125511 @default.
- W2792694550 cites W2092555653 @default.
- W2792694550 cites W2094665036 @default.
- W2792694550 cites W209870406 @default.
- W2792694550 cites W2104571730 @default.
- W2792694550 cites W2105158509 @default.
- W2792694550 cites W2113116917 @default.
- W2792694550 cites W2114918609 @default.
- W2792694550 cites W2117936285 @default.
- W2792694550 cites W2127709168 @default.
- W2792694550 cites W2131350133 @default.
- W2792694550 cites W2145538332 @default.
- W2792694550 cites W2156243411 @default.
- W2792694550 cites W2160357565 @default.
- W2792694550 cites W2165419593 @default.
- W2792694550 cites W2261264953 @default.
- W2792694550 cites W2273938306 @default.
- W2792694550 cites W2293781883 @default.
- W2792694550 cites W2318499983 @default.
- W2792694550 cites W2319621644 @default.
- W2792694550 cites W2329591111 @default.
- W2792694550 cites W2337537669 @default.
- W2792694550 cites W2396088680 @default.
- W2792694550 cites W2405907395 @default.
- W2792694550 cites W2416677583 @default.
- W2792694550 cites W2419299810 @default.
- W2792694550 cites W2472730726 @default.
- W2792694550 cites W2536469737 @default.
- W2792694550 cites W2591853071 @default.
- W2792694550 cites W2742408484 @default.
- W2792694550 cites W2742793893 @default.
- W2792694550 cites W2770485020 @default.
- W2792694550 cites W977157258 @default.
- W2792694550 cites W999964607 @default.
- W2792694550 doi "https://doi.org/10.1016/j.poly.2018.02.008" @default.
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