FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2792695541> ?p ?o ?g. }

• W2792695541 endingPage "1282" @default.
• W2792695541 startingPage "1273" @default.
• W2792695541 abstract "Osseointegrated implants have been recognized as being very reliable and having long-term predictability. However, host defense mechanisms against infection have been known to be impaired around a dental implant because of the lack of a periodontal ligament (PDL). The purpose of our experimental design was to produce cementum and PDL on the implant surface adopting cell sheet technology. To this aim we used PDL-derived cells, which contain multipotential stem cells, as the cell source and we cultured them on an implant material constituted of commercially pure titanium treated with acid etching, blasting, and a calcium phosphate (CaP) coating to improve cell attachment. Implants with adhered human PDL cell sheets were transplanted into bone defects in athymic rat femurs as a xenogeneic model. Implants with adhered canine PDL-derived cell sheets were transplanted into canine mandibular bone as an autologous model. We confirmed that PDL-derived cells cultured with osteoinductive medium had the ability to induce cementum formation. The attachment of PDL cells onto the titanium surface with three surface treatments was accelerated, compared with that onto the smooth titanium surface, at 40 min after starting incubation. Results in the rat model showed that cementum-like and PDL-like tissue was partly observed on the titanium surface with three surface treatments in combination with adherent PDL-derived cell sheets. On the other hand, osseointegration was observed on almost all areas of the smooth titanium surface that had PDL-derived cell sheets, but did not have the three surface treatments. In the canine model, histological observation indicated that formation of cementum-like and PDL-like tissue was induced on the titanium surface with surface treatments and that the PDL-like tissue was perpendicularly oriented between the titanium surface with cementum-like tissue and the bone. Results demonstrate that a periodontal-like structure was formed around a titanium implant, which is similar to the environment existing around a natural tooth. The clinical application of dental implants combined with a cell sheet technique may be feasible as an alternative implant therapy. Furthermore, application of this methodology may play an innovative role in the periodontal, prosthetic, and orthodontic fields in dentistry." @default.
• W2792695541 created "2018-03-29" @default.
• W2792695541 creator A5018567359 @default.
• W2792695541 creator A5021209820 @default.
• W2792695541 creator A5036359047 @default.
• W2792695541 creator A5038488259 @default.
• W2792695541 creator A5039876232 @default.
• W2792695541 creator A5046565682 @default.
• W2792695541 creator A5056873611 @default.
• W2792695541 creator A5069086962 @default.
• W2792695541 creator A5072302802 @default.
• W2792695541 creator A5079495799 @default.
• W2792695541 creator A5080337864 @default.
• W2792695541 creator A5089896651 @default.
• W2792695541 date "2018-08-01" @default.
• W2792695541 modified "2023-10-16" @default.
• W2792695541 title "<i>In Vivo</i> Periodontium Formation Around Titanium Implants Using Periodontal Ligament Cell Sheet" @default.
• W2792695541 cites W101223270 @default.
• W2792695541 cites W1499623758 @default.
• W2792695541 cites W1581621599 @default.
• W2792695541 cites W1862962880 @default.
• W2792695541 cites W1920403669 @default.
• W2792695541 cites W1964070906 @default.
• W2792695541 cites W1965630124 @default.
• W2792695541 cites W1968760803 @default.
• W2792695541 cites W1975471033 @default.
• W2792695541 cites W1980780439 @default.
• W2792695541 cites W1987870530 @default.
• W2792695541 cites W1999301154 @default.
• W2792695541 cites W2010690419 @default.
• W2792695541 cites W2024956861 @default.
• W2792695541 cites W2056773589 @default.
• W2792695541 cites W2057009044 @default.
• W2792695541 cites W2066506855 @default.
• W2792695541 cites W2069256615 @default.
• W2792695541 cites W2072268094 @default.
• W2792695541 cites W2084745162 @default.
• W2792695541 cites W2085436094 @default.
• W2792695541 cites W2099941232 @default.
• W2792695541 cites W2107277218 @default.
• W2792695541 cites W2120917305 @default.
• W2792695541 cites W2123630792 @default.
• W2792695541 cites W2129316319 @default.
• W2792695541 cites W2132722126 @default.
• W2792695541 cites W2144224215 @default.
• W2792695541 cites W2153626578 @default.
• W2792695541 cites W2171223281 @default.
• W2792695541 cites W2197576313 @default.
• W2792695541 cites W2519633942 @default.
• W2792695541 cites W2537492237 @default.
• W2792695541 cites W2604303692 @default.
• W2792695541 cites W2741919972 @default.
• W2792695541 doi "https://doi.org/10.1089/ten.tea.2017.0405" @default.
• W2792695541 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29495925" @default.
• W2792695541 hasPublicationYear "2018" @default.
• W2792695541 type Work @default.
• W2792695541 sameAs 2792695541 @default.
• W2792695541 citedByCount "31" @default.
• W2792695541 countsByYear W27926955412019 @default.
• W2792695541 countsByYear W27926955412020 @default.
• W2792695541 countsByYear W27926955412021 @default.
• W2792695541 countsByYear W27926955412022 @default.
• W2792695541 countsByYear W27926955412023 @default.
• W2792695541 crossrefType "journal-article" @default.
• W2792695541 hasAuthorship W2792695541A5018567359 @default.
• W2792695541 hasAuthorship W2792695541A5021209820 @default.
• W2792695541 hasAuthorship W2792695541A5036359047 @default.
• W2792695541 hasAuthorship W2792695541A5038488259 @default.
• W2792695541 hasAuthorship W2792695541A5039876232 @default.
• W2792695541 hasAuthorship W2792695541A5046565682 @default.
• W2792695541 hasAuthorship W2792695541A5056873611 @default.
• W2792695541 hasAuthorship W2792695541A5069086962 @default.
• W2792695541 hasAuthorship W2792695541A5072302802 @default.
• W2792695541 hasAuthorship W2792695541A5079495799 @default.
• W2792695541 hasAuthorship W2792695541A5080337864 @default.
• W2792695541 hasAuthorship W2792695541A5089896651 @default.
• W2792695541 hasConcept C101414908 @default.
• W2792695541 hasConcept C136229726 @default.
• W2792695541 hasConcept C141071460 @default.
• W2792695541 hasConcept C185592680 @default.
• W2792695541 hasConcept C191897082 @default.
• W2792695541 hasConcept C192562407 @default.
• W2792695541 hasConcept C199343813 @default.
• W2792695541 hasConcept C2777894202 @default.
• W2792695541 hasConcept C2778380114 @default.
• W2792695541 hasConcept C2779263046 @default.
• W2792695541 hasConcept C2781411149 @default.
• W2792695541 hasConcept C41868710 @default.
• W2792695541 hasConcept C506065880 @default.
• W2792695541 hasConcept C71924100 @default.
• W2792695541 hasConceptScore W2792695541C101414908 @default.
• W2792695541 hasConceptScore W2792695541C136229726 @default.
• W2792695541 hasConceptScore W2792695541C141071460 @default.
• W2792695541 hasConceptScore W2792695541C185592680 @default.
• W2792695541 hasConceptScore W2792695541C191897082 @default.
• W2792695541 hasConceptScore W2792695541C192562407 @default.
• W2792695541 hasConceptScore W2792695541C199343813 @default.
• W2792695541 hasConceptScore W2792695541C2777894202 @default.

• next