FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2792935194> ?p ?o ?g. }

• W2792935194 endingPage "11" @default.
• W2792935194 startingPage "1" @default.
• W2792935194 abstract "The aim of this study was to evaluate the effect of upfront combination therapy with ambrisentan and tadalafil on left ventricular (LV) and right ventricular (RV) function in patients with systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH). LV and RV peak longitudinal and circumferential strain and strain rate (SR), which consisted of peak systolic SR (SRs), peak early diastolic SR (SRe), and peak atrial-diastolic SR (SRa) were analyzed using cardiac magnetic resonance imaging (CMRI) data from the recently published ATPAHSS-O trial (ambrisentan and tadalafil upfront combination therapy in SSc-PAH). Twenty-one patients completed the study protocol. Measures of RV systolic function (RV free wall [RVFW] peak longitudinal strain [pLS], RVFW peak longitudinal SRs [pLSRs]) and RV diastolic function (RVFW peak longitudinal SRa [pLSRa], RVFW peak circumferential SRe) were improved after treatment. LV systolic function (LV peak global longitudinal strain [pGLS]) and diastolic function (LV peak global longitudinal SRe [pGLSRe]) were also significantly improved at follow-up. Increased 6-min walk distance was significantly correlated with RVFW pLS and pLSRs, while the decrease in N-terminal pro-brain natriuretic peptide was correlated with LV pGLS. Increased cardiac index was associated with improved LV pGLSRe, and reduction in mean right atrial pressure was correlated with improved RVFW pLS and pLSRa. Combination therapy was associated with a significant improvement in both RV and LV function as assessed by CMR-derived strain and SR. Importantly, the improvement in RV and LV strain and SR correlated with improvements in known prognostic markers of PAH. (Approved by clinicaltrials.gov [NCT01042158] before patient recruitment.)." @default.
• W2792935194 created "2018-03-29" @default.
• W2792935194 creator A5000399886 @default.
• W2792935194 creator A5001475964 @default.
• W2792935194 creator A5008300878 @default.
• W2792935194 creator A5017257299 @default.
• W2792935194 creator A5025484923 @default.
• W2792935194 creator A5027583775 @default.
• W2792935194 creator A5027687662 @default.
• W2792935194 creator A5028259989 @default.
• W2792935194 creator A5033758604 @default.
• W2792935194 creator A5038689387 @default.
• W2792935194 creator A5049579219 @default.
• W2792935194 creator A5050556570 @default.
• W2792935194 creator A5050937401 @default.
• W2792935194 creator A5057720401 @default.
• W2792935194 creator A5060820801 @default.
• W2792935194 creator A5071332365 @default.
• W2792935194 creator A5081661833 @default.
• W2792935194 creator A5089492738 @default.
• W2792935194 date "2018-01-01" @default.
• W2792935194 modified "2023-10-12" @default.
• W2792935194 title "The impact of ambrisentan and tadalafil upfront combination therapy on cardiac function in scleroderma associated pulmonary arterial hypertension patients: cardiac magnetic resonance feature tracking study" @default.
• W2792935194 cites W104761892 @default.
• W2792935194 cites W1536978542 @default.
• W2792935194 cites W189373267 @default.
• W2792935194 cites W1936073859 @default.
• W2792935194 cites W1978545009 @default.
• W2792935194 cites W1987898978 @default.
• W2792935194 cites W2004733118 @default.
• W2792935194 cites W2009923801 @default.
• W2792935194 cites W2017805629 @default.
• W2792935194 cites W2032885711 @default.
• W2792935194 cites W2050644659 @default.
• W2792935194 cites W2051069436 @default.
• W2792935194 cites W2064874816 @default.
• W2792935194 cites W2073768923 @default.
• W2792935194 cites W2077473348 @default.
• W2792935194 cites W2096546669 @default.
• W2792935194 cites W2108497894 @default.
• W2792935194 cites W2109488825 @default.
• W2792935194 cites W2113003320 @default.
• W2792935194 cites W2113479704 @default.
• W2792935194 cites W2118077848 @default.
• W2792935194 cites W2118210486 @default.
• W2792935194 cites W2120493345 @default.
• W2792935194 cites W2121376498 @default.
• W2792935194 cites W2124549031 @default.
• W2792935194 cites W2134006584 @default.
• W2792935194 cites W2137071299 @default.
• W2792935194 cites W2138124880 @default.
• W2792935194 cites W2143241675 @default.
• W2792935194 cites W2144842858 @default.
• W2792935194 cites W2147232111 @default.
• W2792935194 cites W2149839143 @default.
• W2792935194 cites W2152468817 @default.
• W2792935194 cites W2155368717 @default.
• W2792935194 cites W2165317591 @default.
• W2792935194 cites W2187887962 @default.
• W2792935194 cites W2516408494 @default.
• W2792935194 cites W2546447965 @default.
• W2792935194 cites W2547828373 @default.
• W2792935194 cites W2548159990 @default.
• W2792935194 cites W289694434 @default.
• W2792935194 doi "https://doi.org/10.1177/2045893217748307" @default.
• W2792935194 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6018906" @default.
• W2792935194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29251556" @default.
• W2792935194 hasPublicationYear "2018" @default.
• W2792935194 type Work @default.
• W2792935194 sameAs 2792935194 @default.
• W2792935194 citedByCount "29" @default.
• W2792935194 countsByYear W27929351942018 @default.
• W2792935194 countsByYear W27929351942019 @default.
• W2792935194 countsByYear W27929351942020 @default.
• W2792935194 countsByYear W27929351942021 @default.
• W2792935194 countsByYear W27929351942022 @default.
• W2792935194 countsByYear W27929351942023 @default.
• W2792935194 crossrefType "journal-article" @default.
• W2792935194 hasAuthorship W2792935194A5000399886 @default.
• W2792935194 hasAuthorship W2792935194A5001475964 @default.
• W2792935194 hasAuthorship W2792935194A5008300878 @default.
• W2792935194 hasAuthorship W2792935194A5017257299 @default.
• W2792935194 hasAuthorship W2792935194A5025484923 @default.
• W2792935194 hasAuthorship W2792935194A5027583775 @default.
• W2792935194 hasAuthorship W2792935194A5027687662 @default.
• W2792935194 hasAuthorship W2792935194A5028259989 @default.
• W2792935194 hasAuthorship W2792935194A5033758604 @default.
• W2792935194 hasAuthorship W2792935194A5038689387 @default.
• W2792935194 hasAuthorship W2792935194A5049579219 @default.
• W2792935194 hasAuthorship W2792935194A5050556570 @default.
• W2792935194 hasAuthorship W2792935194A5050937401 @default.
• W2792935194 hasAuthorship W2792935194A5057720401 @default.
• W2792935194 hasAuthorship W2792935194A5060820801 @default.
• W2792935194 hasAuthorship W2792935194A5071332365 @default.
• W2792935194 hasAuthorship W2792935194A5081661833 @default.
• W2792935194 hasAuthorship W2792935194A5089492738 @default.
• W2792935194 hasBestOaLocation W27929351941 @default.
• W2792935194 hasConcept C111566952 @default.

• next