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- W2793093427 abstract "T wo samples of Tanacetum praeteritum (Horwood) Heywood subsp. praeteritum (Horwood) were collected in flowering period and subjected separately to hydrodistillation to yield the essential oils (A and B). The oils were investigated for chemical composition with GC-FID and GC/MS techniques and evaluated against acetylcholinesterase and a -amylase enzymes and free radicals (DPPH • and ABTS •+ ) using microtiter plate assays. Both of the oils were characterized with high abundance of oxygenated monoterpenes. The oils were distinguished by the main constituents, namely, camphor (37.6 %), 1,8-cineole (19.5 %) and terpinen-4-ol (9.3 %) were found as the major constituents in the oil A, while a -thujone (79.4 %) and b -thujone (8.5 %) were detected in the oil B. The oils demonstrated significant inhibitory (80 % and 60.0 %) potentials on acetylcholinesterase (an IC 50 of 0.74 mg/mL and an IC 50 of 1.78 mg/mL, respectively) which involved into Alzheimer’s disease. With respect to antidiabetic activity, the oils demonstrated significant inhibiting potential on porcine pancreatic a -amylase (an IC 50 of 1.02 mg/mL and an IC 50 of 0.89 mg/mL) in I 2 /KI assay. The oils demonstrated weak free radical scavenging activity against DPPH radicals and moderate activity (0.23 mM and 0.15 mM) against ABTS +• in TEAC assay." @default.
- W2793093427 created "2018-03-29" @default.
- W2793093427 creator A5043706974 @default.
- W2793093427 date "2018-03-09" @default.
- W2793093427 modified "2023-09-27" @default.
- W2793093427 title "Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils" @default.
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- W2793093427 doi "https://doi.org/10.18596/jotcsa.389075" @default.
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