FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2793142512> ?p ?o ?g. }

• W2793142512 endingPage "1044" @default.
• W2793142512 startingPage "1039" @default.
• W2793142512 abstract "Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease that occurs worldwide in both children and adults, with different disease manifestations, activity and severity between them. Objectives To analyse the difference in disease onset patterns and activity in Egyptian children and adults with SLE. Methods A retrospective cohort study conducted on 298 Egyptian SLE patients, 215 adults (a-SLE) (>18 years) and 83 children (j-SLE) (≤18 years). Disease onset, clinical manifestations and laboratory investigations were recorded. The systemic lupus erythematosus disease activity index (SLEDAI) was used to assess disease onset activity; renal biopsy was performed for all cases affected with renal symptoms. Results A total of 215 a-SLE (F/M: 14.4/1), mean age 29.65 ± 10.235 years, and 83 j-SLE (F/M: 5.4/1), mean age at diagnosis 12.63 ± 3.112 years. The most frequent initial a-SLE symptoms were constitutional (88.8%), mucocutaneous (71.2%), haematological (64.2%), articular (62.3%), renal (43.7%), vascular (15.3%), serositis (14.4%) and finally central nervous system (11.6%). There were no significant differences between a-SLE and j-SLE with regard to constitutional, mucocutaneous, renal, vascular and serositis manifestations, which were 92.8%, 74.7%, 53%, 16.9% and 10.8%, respectively, but the j-SLE haematological (88%) and central nervous system (30.1%) manifestations were significantly higher than a-SLE and articular manifestations were significantly lower in j-SLE (14.5%) than a-SLE. Antinuclear antibodies were positive for 95.3% of a-SLE and 97.6% of j-SLE. Anti-dsDNA was positive for 84.7% a-SLE and was significantly higher in j-SLE (92.8%). The SLEDAI score was 12.23 ± 4.966 in a-SLE and was significantly higher in j-SLE (27.13 ± 19.968). International Society of Nephrology lupus nephritis classes III and IV (42.4%) were the commonest findings in a-SLE; however, classes I and III (57.9%) were the commonest in j-SLE. Conclusions SLE had a wide variety of clinical and immunological manifestations, with some similarity and differences between a-SLE and j-SLE; juvenile onset lupus had a higher SLEDAI with more aggressive initial manifestations than a-SLE." @default.
• W2793142512 created "2018-03-29" @default.
• W2793142512 creator A5021370295 @default.
• W2793142512 creator A5075444249 @default.
• W2793142512 date "2018-02-20" @default.
• W2793142512 modified "2023-10-14" @default.
• W2793142512 title "Comparison between disease onset patterns of Egyptian juvenile and adult systemic lupus erythematosus (single centre experience)" @default.
• W2793142512 cites W116702950 @default.
• W2793142512 cites W1965425972 @default.
• W2793142512 cites W1972063433 @default.
• W2793142512 cites W1972737260 @default.
• W2793142512 cites W1975743269 @default.
• W2793142512 cites W1978143823 @default.
• W2793142512 cites W1982134628 @default.
• W2793142512 cites W1982569518 @default.
• W2793142512 cites W1995365224 @default.
• W2793142512 cites W2002958926 @default.
• W2793142512 cites W2010980252 @default.
• W2793142512 cites W2026559290 @default.
• W2793142512 cites W2029539106 @default.
• W2793142512 cites W2038600011 @default.
• W2793142512 cites W2052240769 @default.
• W2793142512 cites W2053393898 @default.
• W2793142512 cites W2063621190 @default.
• W2793142512 cites W2064472094 @default.
• W2793142512 cites W2070527591 @default.
• W2793142512 cites W2073090648 @default.
• W2793142512 cites W2087785715 @default.
• W2793142512 cites W2114638396 @default.
• W2793142512 cites W2122944129 @default.
• W2793142512 cites W2124179873 @default.
• W2793142512 cites W2135758472 @default.
• W2793142512 cites W2138889351 @default.
• W2793142512 cites W2150729784 @default.
• W2793142512 cites W2159860161 @default.
• W2793142512 doi "https://doi.org/10.1177/0961203318760208" @default.
• W2793142512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29460702" @default.
• W2793142512 hasPublicationYear "2018" @default.
• W2793142512 type Work @default.
• W2793142512 sameAs 2793142512 @default.
• W2793142512 citedByCount "11" @default.
• W2793142512 countsByYear W27931425122018 @default.
• W2793142512 countsByYear W27931425122019 @default.
• W2793142512 countsByYear W27931425122020 @default.
• W2793142512 countsByYear W27931425122021 @default.
• W2793142512 countsByYear W27931425122022 @default.
• W2793142512 countsByYear W27931425122023 @default.
• W2793142512 crossrefType "journal-article" @default.
• W2793142512 hasAuthorship W2793142512A5021370295 @default.
• W2793142512 hasAuthorship W2793142512A5075444249 @default.
• W2793142512 hasConcept C126322002 @default.
• W2793142512 hasConcept C149443304 @default.
• W2793142512 hasConcept C156662089 @default.
• W2793142512 hasConcept C159654299 @default.
• W2793142512 hasConcept C163764329 @default.
• W2793142512 hasConcept C203014093 @default.
• W2793142512 hasConcept C2776820843 @default.
• W2793142512 hasConcept C2776912625 @default.
• W2793142512 hasConcept C2777165109 @default.
• W2793142512 hasConcept C2777753580 @default.
• W2793142512 hasConcept C2779134260 @default.
• W2793142512 hasConcept C2779912601 @default.
• W2793142512 hasConcept C71924100 @default.
• W2793142512 hasConcept C72563966 @default.
• W2793142512 hasConcept C90924648 @default.
• W2793142512 hasConceptScore W2793142512C126322002 @default.
• W2793142512 hasConceptScore W2793142512C149443304 @default.
• W2793142512 hasConceptScore W2793142512C156662089 @default.
• W2793142512 hasConceptScore W2793142512C159654299 @default.
• W2793142512 hasConceptScore W2793142512C163764329 @default.
• W2793142512 hasConceptScore W2793142512C203014093 @default.
• W2793142512 hasConceptScore W2793142512C2776820843 @default.
• W2793142512 hasConceptScore W2793142512C2776912625 @default.
• W2793142512 hasConceptScore W2793142512C2777165109 @default.
• W2793142512 hasConceptScore W2793142512C2777753580 @default.
• W2793142512 hasConceptScore W2793142512C2779134260 @default.
• W2793142512 hasConceptScore W2793142512C2779912601 @default.
• W2793142512 hasConceptScore W2793142512C71924100 @default.
• W2793142512 hasConceptScore W2793142512C72563966 @default.
• W2793142512 hasConceptScore W2793142512C90924648 @default.
• W2793142512 hasIssue "6" @default.
• W2793142512 hasLocation W27931425121 @default.
• W2793142512 hasLocation W27931425122 @default.
• W2793142512 hasOpenAccess W2793142512 @default.
• W2793142512 hasPrimaryLocation W27931425121 @default.
• W2793142512 hasRelatedWork W2064628430 @default.
• W2793142512 hasRelatedWork W2093797968 @default.
• W2793142512 hasRelatedWork W2793142512 @default.
• W2793142512 hasRelatedWork W2939418848 @default.
• W2793142512 hasRelatedWork W2952961586 @default.
• W2793142512 hasRelatedWork W2953634127 @default.
• W2793142512 hasRelatedWork W3162655739 @default.
• W2793142512 hasRelatedWork W3210773484 @default.
• W2793142512 hasRelatedWork W4205136104 @default.
• W2793142512 hasRelatedWork W2184182387 @default.
• W2793142512 hasVolume "27" @default.
• W2793142512 isParatext "false" @default.
• W2793142512 isRetracted "false" @default.

• next