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- W2793158312 endingPage "1788" @default.
- W2793158312 startingPage "1785" @default.
- W2793158312 abstract "We developed a novel method for synthesizing 2‐(4‐hydroxyaryl)‐3,4‐fused tricyclic dihydrobenzopyrans with 2,3‐ syn and 3,4‐ syn motif based on the acid‐promoted cascade cyclization via vinylidene para ‐quinone methide intermediates. Using easily prepared linear substrates, TFA‐promoted cascade cyclization proceeded in the presence of triethylsilane, affording a series of five to seven‐membered ring‐fused dihydrobenzopyran derivatives in moderate to excellent yield in a highly diastereoselective manner. The developed method provided new access to potent and selective ERβ agonists." @default.
- W2793158312 created "2018-03-29" @default.
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- W2793158312 date "2018-04-19" @default.
- W2793158312 modified "2023-09-30" @default.
- W2793158312 title "Acid-Promoted Cascade Cyclization to Produce 2-(4′-Alkoxyaryl)-3,4-Fused Tricyclic Dihydrobenzopyrans via a Vinylidene <i>para-</i> Quinone Methide Intermediate" @default.
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- W2793158312 doi "https://doi.org/10.1002/ejoc.201800013" @default.
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