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• W2793238212 abstract "Regulation of Bio-systems in a clean, simple, and efficient way is important for the design of smart bio-interfaces and bioelectronic devices. Light as a non-invasive mean to control the activity of a protein enables spatial and temporal control far superior to other chemical and physical methods. The ability to regulate the activity of a catalytic enzyme in a biofuel-cell reduces the waste of resources and energy and turns the fuel-cell into a smart and more efficient device for power generation. Here we present a microbial-fuel-cell based on a surface displayed, photo-switchable alcohol dehydrogenase. The enzyme was modified near the active site using non-canonical amino acids and a small photo-reactive molecule, which enables reversible control of enzymatic activity. Depending on the modification site, the enzyme exhibits reversible behavior upon irradiation with UV and visible light, in both biochemical, and electrochemical assays. The change observed in power output of a microbial fuel cell utilizing the modified enzyme was almost five-fold, between inactive and active states." @default.
• W2793238212 created "2018-03-29" @default.
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• W2793238212 date "2018-02-26" @default.
• W2793238212 modified "2023-09-25" @default.
• W2793238212 title "Photo-switchable microbial fuel-cells" @default.
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• W2793238212 doi "https://doi.org/10.1002/bit.26555" @default.
• W2793238212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29411858" @default.
• W2793238212 hasPublicationYear "2018" @default.
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