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- W2793258488 abstract "Many semi-volatile organic compounds (SVOCs), suspected of reprotoxic, neurotoxic or carcinogenic effects, were measured in indoor settled dust. Dust ingestion is a non-negligible pathway of exposure to some of these SVOCs, and an accurate knowledge of the real exposure is necessary for a better evaluation of health risks. To this end, the bioaccessibility of SVOCs in dust needs to be considered. In the present work, bioaccessibility measurement methods, SVOCs’ oral bioaccessibility data and influencing factors were reviewed. SVOC bioaccessibilities (%) ranged from 11 to 94, 8 to 100, 3 to 92, 1 to 81, 6 to 52, and 2 to 17, for brominated flame retardants, organophosphorus flame retardants, polychlorobiphenyls, phthalates, pesticides and polycyclic aromatic hydrocarbons, respectively. Measurements method produced varying results depending on the inclusion of food and/or sink in the model. Characteristics of dust, e.g., organic matter content and particle size, also influenced bioaccessibility data. Last, results were influenced by SVOC properties, such as octanol/water partition coefficient and migration pathway into dust. Factors related to dust and SVOCs could be used in prediction models. To this end, more bioaccessibility studies covering more substances should be performed, using methods that are harmonized and validated by comparison to in-vivo studies." @default.
- W2793258488 created "2018-03-29" @default.
- W2793258488 creator A5005285252 @default.
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- W2793258488 creator A5052401250 @default.
- W2793258488 creator A5056441781 @default.
- W2793258488 creator A5073911230 @default.
- W2793258488 date "2018-06-01" @default.
- W2793258488 modified "2023-10-18" @default.
- W2793258488 title "Oral bioaccessibility of semi-volatile organic compounds (SVOCs) in settled dust: A review of measurement methods, data and influencing factors" @default.
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- W2793258488 doi "https://doi.org/10.1016/j.jhazmat.2018.03.035" @default.
- W2793258488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29621676" @default.
- W2793258488 hasPublicationYear "2018" @default.
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