Matches in SemOpenAlex for { <https://semopenalex.org/work/W2793365023> ?p ?o ?g. }
- W2793365023 endingPage "530" @default.
- W2793365023 startingPage "521" @default.
- W2793365023 abstract "The placenta is a vital organ providing the developing fetus with nutrient and gas exchange, thermoregulation, and waste elimination necessary for fetal development, as well as producing hormones to maintain pregnancy. It is hypothesized that fetal pig death in porcine reproductive and respiratory syndrome may be attributed to pathology of the maternal-fetal interface leading to premature placental separation. This study was designed to evaluate the chronologic progression of porcine reproductive and respiratory syndrome virus (PRRSV)–induced lesions at the maternal-fetal interface, with particular focus on placental separation in experimentally challenged third-trimester gilts. Fifteen gilts were inoculated with a virulent strain of PRRSV-2 on gestation day 86 ± 0.4. On multiple days postinoculation, 3 gilts along with 1 sham-inoculated control per time point were euthanized, and uterine and fetal placental tissues corresponding to each fetus were collected for histopathologic evaluation. The presence of any fetal lesion was 23 times more likely in compromised (meconium-stained and decomposed) compared with viable fetuses ( P < .001). In PRRSV-infected gilts, endometritis was more severe than placentitis, and the severity of endometrial inflammation and vasculitis increased progressively from 2 to 14 days postinoculation. Neither placental vasculitis nor a chronologic progression in the severity of placental detachment was observed. Severe placental detachment was more frequently present in PRRSV-infected compared with noninfected samples and was most significantly associated with placental inflammation, compared with other uterine lesions, viral load, or termination day. The results of this study suggest that placental separation by itself is not sufficient to significantly compromise fetal viability in reproductive porcine reproductive and respiratory syndrome." @default.
- W2793365023 created "2018-03-29" @default.
- W2793365023 creator A5008581083 @default.
- W2793365023 creator A5014958059 @default.
- W2793365023 creator A5017881077 @default.
- W2793365023 creator A5060372105 @default.
- W2793365023 creator A5077058731 @default.
- W2793365023 creator A5089333055 @default.
- W2793365023 date "2018-03-22" @default.
- W2793365023 modified "2023-10-16" @default.
- W2793365023 title "Histologic Changes Associated With Placental Separation in Gilts Infected with Porcine Reproductive and Respiratory Syndrome Virus" @default.
- W2793365023 cites W1532846469 @default.
- W2793365023 cites W1942354472 @default.
- W2793365023 cites W1993591156 @default.
- W2793365023 cites W2021751941 @default.
- W2793365023 cites W2028919864 @default.
- W2793365023 cites W2033792267 @default.
- W2793365023 cites W2040930725 @default.
- W2793365023 cites W2042643759 @default.
- W2793365023 cites W2050082928 @default.
- W2793365023 cites W2071475899 @default.
- W2793365023 cites W2073008636 @default.
- W2793365023 cites W2082068419 @default.
- W2793365023 cites W2086852038 @default.
- W2793365023 cites W2099095026 @default.
- W2793365023 cites W2102272195 @default.
- W2793365023 cites W2129620275 @default.
- W2793365023 cites W2144435541 @default.
- W2793365023 cites W2149383095 @default.
- W2793365023 cites W2150786270 @default.
- W2793365023 cites W2164707968 @default.
- W2793365023 cites W2170630161 @default.
- W2793365023 cites W2293283196 @default.
- W2793365023 cites W2401866185 @default.
- W2793365023 cites W2492572977 @default.
- W2793365023 cites W2592714339 @default.
- W2793365023 cites W2594120567 @default.
- W2793365023 doi "https://doi.org/10.1177/0300985818765067" @default.
- W2793365023 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29566610" @default.
- W2793365023 hasPublicationYear "2018" @default.
- W2793365023 type Work @default.
- W2793365023 sameAs 2793365023 @default.
- W2793365023 citedByCount "11" @default.
- W2793365023 countsByYear W27933650232018 @default.
- W2793365023 countsByYear W27933650232019 @default.
- W2793365023 countsByYear W27933650232020 @default.
- W2793365023 countsByYear W27933650232021 @default.
- W2793365023 countsByYear W27933650232022 @default.
- W2793365023 countsByYear W27933650232023 @default.
- W2793365023 crossrefType "journal-article" @default.
- W2793365023 hasAuthorship W2793365023A5008581083 @default.
- W2793365023 hasAuthorship W2793365023A5014958059 @default.
- W2793365023 hasAuthorship W2793365023A5017881077 @default.
- W2793365023 hasAuthorship W2793365023A5060372105 @default.
- W2793365023 hasAuthorship W2793365023A5077058731 @default.
- W2793365023 hasAuthorship W2793365023A5089333055 @default.
- W2793365023 hasBestOaLocation W27933650231 @default.
- W2793365023 hasConcept C134018914 @default.
- W2793365023 hasConcept C142724271 @default.
- W2793365023 hasConcept C16685009 @default.
- W2793365023 hasConcept C172680121 @default.
- W2793365023 hasConcept C203014093 @default.
- W2793365023 hasConcept C2522874641 @default.
- W2793365023 hasConcept C2776015282 @default.
- W2793365023 hasConcept C2776914184 @default.
- W2793365023 hasConcept C2776953305 @default.
- W2793365023 hasConcept C2777629866 @default.
- W2793365023 hasConcept C2779066055 @default.
- W2793365023 hasConcept C2779134260 @default.
- W2793365023 hasConcept C2779234561 @default.
- W2793365023 hasConcept C2779819720 @default.
- W2793365023 hasConcept C2781156865 @default.
- W2793365023 hasConcept C42407357 @default.
- W2793365023 hasConcept C46973012 @default.
- W2793365023 hasConcept C54355233 @default.
- W2793365023 hasConcept C71924100 @default.
- W2793365023 hasConcept C86803240 @default.
- W2793365023 hasConceptScore W2793365023C134018914 @default.
- W2793365023 hasConceptScore W2793365023C142724271 @default.
- W2793365023 hasConceptScore W2793365023C16685009 @default.
- W2793365023 hasConceptScore W2793365023C172680121 @default.
- W2793365023 hasConceptScore W2793365023C203014093 @default.
- W2793365023 hasConceptScore W2793365023C2522874641 @default.
- W2793365023 hasConceptScore W2793365023C2776015282 @default.
- W2793365023 hasConceptScore W2793365023C2776914184 @default.
- W2793365023 hasConceptScore W2793365023C2776953305 @default.
- W2793365023 hasConceptScore W2793365023C2777629866 @default.
- W2793365023 hasConceptScore W2793365023C2779066055 @default.
- W2793365023 hasConceptScore W2793365023C2779134260 @default.
- W2793365023 hasConceptScore W2793365023C2779234561 @default.
- W2793365023 hasConceptScore W2793365023C2779819720 @default.
- W2793365023 hasConceptScore W2793365023C2781156865 @default.
- W2793365023 hasConceptScore W2793365023C42407357 @default.
- W2793365023 hasConceptScore W2793365023C46973012 @default.
- W2793365023 hasConceptScore W2793365023C54355233 @default.
- W2793365023 hasConceptScore W2793365023C71924100 @default.
- W2793365023 hasConceptScore W2793365023C86803240 @default.
- W2793365023 hasIssue "4" @default.