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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2793407627> ?p ?o ?g. }

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• W2793407627 abstract "A second-generation small molecule P2X3 receptor antagonist has been developed. The lead optimization strategy to address shortcomings of the first-generation preclinical lead compound is described herein. These studies were directed towards the identification and amelioration of preclinical hepatobiliary findings, reducing potential for drug-drug interactions, and decreasing the projected human dose of the first-generation lead." @default.
• W2793407627 created "2018-03-29" @default.
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• W2793407627 date "2018-05-01" @default.
• W2793407627 modified "2023-09-28" @default.
• W2793407627 title "Identification of second-generation P2X3 antagonists for treatment of pain" @default.
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• W2793407627 doi "https://doi.org/10.1016/j.bmcl.2018.02.039" @default.
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