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- W2793428298 endingPage "182" @default.
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- W2793428298 abstract "Cannabis is the most commonly used substance of abuse in the United States after alcohol and tobacco. With a recent increase in the rates of cannabis use disorder (CUD) and a decrease in the perceived risk of cannabis use, it is imperative to assess the addictive potential of cannabis. Here we evaluate cannabis use through the neurobiological model of addiction proposed by Koob and Volkow. The model proposes that repeated substance abuse drives neurobiological changes in the brain that can be separated into three distinct stages, each of which perpetuates the cycle of addiction. Here we review previous research on the acute and long-term effects of cannabis use on the brain and behavior, and find that the three-stage framework of addiction applies to CUD in a manner similar to other drugs of abuse, albeit with some slight differences. These findings highlight the urgent need to conduct research that elucidates specific neurobiological changes associated with CUD in humans. (©Zehra A, Liuck, Manza P, Wiers CE, Volkow ND Wergh J, 2018. Reprinted with permission from Journal of Neuroimmune Pharmacology (2018) 13:438-452)" @default.
- W2793428298 created "2018-03-29" @default.
- W2793428298 creator A5002969658 @default.
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- W2793428298 creator A5055170056 @default.
- W2793428298 creator A5078891337 @default.
- W2793428298 creator A5081492952 @default.
- W2793428298 date "2019-04-01" @default.
- W2793428298 modified "2023-10-13" @default.
- W2793428298 title "Cannabis Addiction and the Brain: a Review" @default.
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