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- W2793516985 abstract "The rapid global evolution of influenza virus begins with mutations that arise de novo in individual infections, but little is known about how evolution occurs within hosts. We review recent progress in understanding how and why influenza viruses evolve within human hosts. Advances in deep sequencing make it possible to measure within-host genetic diversity in both acute and chronic influenza infections. Factors like antigenic selection, antiviral treatment, tissue specificity, spatial structure, and multiplicity of infection may affect how influenza viruses evolve within human hosts. Studies of within-host evolution can contribute to our understanding of the evolutionary and epidemiological factors that shape influenza virus's global evolution." @default.
- W2793516985 created "2018-03-29" @default.
- W2793516985 creator A5025387674 @default.
- W2793516985 creator A5031042804 @default.
- W2793516985 creator A5076865790 @default.
- W2793516985 creator A5091068534 @default.
- W2793516985 date "2018-09-01" @default.
- W2793516985 modified "2023-10-14" @default.
- W2793516985 title "Within-Host Evolution of Human Influenza Virus" @default.
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