FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2793545486> ?p ?o ?g. }

• W2793545486 abstract "Lipoprotein lipase (LPL) is widely linked to lipid and lipoprotein metabolism, but its effects on coronary artery disease (CAD) are not clearly elucidated. The aim of the present study was to clarify the association between LPL gene polymorphisms and CAD susceptibility. The pooled odds ratio (OR) and 95% confidence interval (CI) were calculated to estimate the strength of the relationship between LPL gene polymorphisms and CAD risk. Comprehensive electronic databases, including PubMed, EMBASE, Web of Science, and the Cochrane Library, were systematically searched. A total of 45 records containing 80 eligible studies were analyzed. The results indicated an increased risk between the LPL D9N polymorphism and susceptibility to CAD in the dominant genetic model (AA + GA vs. GG: OR = 1.46, 95% CI = 1.14–1.87), whereas the LPL HindIII polymorphism showed a protective effect against CAD under all tested models (GG + GT vs. TT: OR = 0.85, 95% CI = 0.75–0.97; GG vs. TT + TG: OR = 0.62, 95% CI = 0.47–0.83; G vs. T: OR = 0.81, 95% CI = 0.71–0.92). No significant association was identified for the LPL N291S and PvuII polymorphisms. Stratification analysis by ethnicity suggested a significant correlation between the LPL S447X polymorphism and CAD susceptibility in Caucasians under the dominant and allele genetic models. In summary, our meta-analysis indicated that the LPL D9N polymorphism was associated with an increased risk of CAD, whereas the S447X and HindIII polymorphisms showed protective effects. There was no association observed between the N291S and PvuII polymorphisms and CAD risk." @default.
• W2793545486 created "2018-03-29" @default.
• W2793545486 creator A5001121694 @default.
• W2793545486 creator A5018863416 @default.
• W2793545486 creator A5032841164 @default.
• W2793545486 creator A5042784783 @default.
• W2793545486 creator A5044079093 @default.
• W2793545486 date "2018-03-16" @default.
• W2793545486 modified "2023-10-16" @default.
• W2793545486 title "Associations between <i>LPL</i> gene polymorphisms and coronary artery disease: evidence based on an updated and cumulative meta-analysis" @default.
• W2793545486 cites W1575441863 @default.
• W2793545486 cites W1677356992 @default.
• W2793545486 cites W1827092840 @default.
• W2793545486 cites W1911300180 @default.
• W2793545486 cites W1930505975 @default.
• W2793545486 cites W1935359412 @default.
• W2793545486 cites W1975960142 @default.
• W2793545486 cites W1979423827 @default.
• W2793545486 cites W1979898984 @default.
• W2793545486 cites W1980173564 @default.
• W2793545486 cites W1983049756 @default.
• W2793545486 cites W1983793079 @default.
• W2793545486 cites W1983972137 @default.
• W2793545486 cites W1984725713 @default.
• W2793545486 cites W1985298634 @default.
• W2793545486 cites W1988227739 @default.
• W2793545486 cites W2001361643 @default.
• W2793545486 cites W2001791354 @default.
• W2793545486 cites W2003283414 @default.
• W2793545486 cites W2006815039 @default.
• W2793545486 cites W2006941659 @default.
• W2793545486 cites W2008331970 @default.
• W2793545486 cites W2011468836 @default.
• W2793545486 cites W2016897888 @default.
• W2793545486 cites W2017147918 @default.
• W2793545486 cites W2027318597 @default.
• W2793545486 cites W2027946236 @default.
• W2793545486 cites W2028517248 @default.
• W2793545486 cites W2029909776 @default.
• W2793545486 cites W2038776814 @default.
• W2793545486 cites W2042355540 @default.
• W2793545486 cites W2050101980 @default.
• W2793545486 cites W2050971515 @default.
• W2793545486 cites W2057494087 @default.
• W2793545486 cites W2067760644 @default.
• W2793545486 cites W2074613407 @default.
• W2793545486 cites W2074883954 @default.
• W2793545486 cites W2082953323 @default.
• W2793545486 cites W2095885613 @default.
• W2793545486 cites W2096504289 @default.
• W2793545486 cites W2099200539 @default.
• W2793545486 cites W2104352098 @default.
• W2793545486 cites W2105435914 @default.
• W2793545486 cites W2113155747 @default.
• W2793545486 cites W2113541456 @default.
• W2793545486 cites W2116431416 @default.
• W2793545486 cites W2116475791 @default.
• W2793545486 cites W2117219849 @default.
• W2793545486 cites W2117933266 @default.
• W2793545486 cites W2126568311 @default.
• W2793545486 cites W2129777959 @default.
• W2793545486 cites W2148550388 @default.
• W2793545486 cites W2152745230 @default.
• W2793545486 cites W2152808481 @default.
• W2793545486 cites W2159531042 @default.
• W2793545486 cites W2167962733 @default.
• W2793545486 cites W2169473251 @default.
• W2793545486 cites W2183205430 @default.
• W2793545486 cites W2186283758 @default.
• W2793545486 cites W2196906371 @default.
• W2793545486 cites W2297126310 @default.
• W2793545486 cites W2345841042 @default.
• W2793545486 cites W2464896206 @default.
• W2793545486 cites W2588681363 @default.
• W2793545486 cites W292535042 @default.
• W2793545486 cites W418844535 @default.
• W2793545486 cites W4234664301 @default.
• W2793545486 cites W4256692001 @default.
• W2793545486 doi "https://doi.org/10.1042/bsr20171642" @default.
• W2793545486 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5857905" @default.
• W2793545486 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29459423" @default.
• W2793545486 hasPublicationYear "2018" @default.
• W2793545486 type Work @default.
• W2793545486 sameAs 2793545486 @default.
• W2793545486 citedByCount "7" @default.
• W2793545486 countsByYear W27935454862019 @default.
• W2793545486 countsByYear W27935454862020 @default.
• W2793545486 countsByYear W27935454862022 @default.
• W2793545486 countsByYear W27935454862023 @default.
• W2793545486 crossrefType "journal-article" @default.
• W2793545486 hasAuthorship W2793545486A5001121694 @default.
• W2793545486 hasAuthorship W2793545486A5018863416 @default.
• W2793545486 hasAuthorship W2793545486A5032841164 @default.
• W2793545486 hasAuthorship W2793545486A5042784783 @default.
• W2793545486 hasAuthorship W2793545486A5044079093 @default.
• W2793545486 hasBestOaLocation W27935454861 @default.
• W2793545486 hasConcept C104317684 @default.
• W2793545486 hasConcept C126322002 @default.
• W2793545486 hasConcept C135763542 @default.
• W2793545486 hasConcept C153209595 @default.

• next