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• W2793632013 abstract "A convergent total synthesis of MK-801 has been achieved. Key synthetic transformations include a multicomponent Barbier-type reaction to construct the α-branched amine, a selective Heck α-coupling tactic to generate the exocyclic alkene skeleton, and a late-stage intramolecular hydroamination reaction between the exocyclic alkene and the secondary protected amine. The efficacy of this method was demonstrated by the synthesis of two news analogues substituted on the aromatic rings." @default.
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• W2793632013 date "2018-02-28" @default.
• W2793632013 modified "2023-10-15" @default.
• W2793632013 title "Convergent Strategy to Dizocilpine MK-801 and Derivatives" @default.
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• W2793632013 doi "https://doi.org/10.1021/acs.joc.8b00305" @default.
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