FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2793649743> ?p ?o ?g. }

• W2793649743 endingPage "1431" @default.
• W2793649743 startingPage "1424" @default.
• W2793649743 abstract "Hematopoietic stem cell transplantation (HSCT) is the only curative option for a subset of patients with high-risk or relapsed acute lymphoblastic leukemia (ALL). Given evolving practices, it is important to continually evaluate outcomes for pediatric ALL following HSCT. Outcomes after HSCT are influenced by the type of donor used as this determines the degree and method of T cell depletion used and, consequently, specific transplant-related morbidities. We retrospectively analyzed HSCT data from our center for transplants performed between January 2008 and May 2016, comparing outcomes among different donor types. One hundred and twenty-four pediatric patients underwent HSCT from a matched sibling donor (MSD; n = 48), an unrelated matched donor (UMD; n = 56), or a haploidentical donor (n = 20). We observed a similar 3-year event-free survival (EFS) for MSD recipients (of .64) and for UMD recipients (.62), but a significantly lower EFS for recipients of haploidentical transplants (.35; P = .01). Relapse was the main cause of HSCT failure and was significantly higher in the haploidentical donor group (.47 versus .19 for MSD and .24 for UMD; P = .02). Treatment-related mortality was evenly distributed among the donor groups (.17, .16, and .15 for the MSD, UMD, and haploidentical groups, respectively). Rates of infection-related mortality were lower than previously reported. Relapse is the main obstacle for successful HSCT in the contemporary era, and this effect is most evident in recipients of haploidentical donor grafts. Newer methods to improve graft-versus-leukemia effect are being evaluated and will need to be incorporated into the management of high-risk patients." @default.
• W2793649743 created "2018-03-29" @default.
• W2793649743 creator A5010413445 @default.
• W2793649743 creator A5021029688 @default.
• W2793649743 creator A5026301065 @default.
• W2793649743 creator A5029941019 @default.
• W2793649743 creator A5032050779 @default.
• W2793649743 creator A5036222762 @default.
• W2793649743 creator A5044253645 @default.
• W2793649743 creator A5056105964 @default.
• W2793649743 creator A5058287032 @default.
• W2793649743 creator A5060751609 @default.
• W2793649743 creator A5061611053 @default.
• W2793649743 creator A5068726940 @default.
• W2793649743 creator A5076234152 @default.
• W2793649743 creator A5088664989 @default.
• W2793649743 date "2018-07-01" @default.
• W2793649743 modified "2023-10-16" @default.
• W2793649743 title "Current Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphocytic Leukemia: Success, Failure and Future Perspectives—A Single-Center Experience, 2008 to 2016" @default.
• W2793649743 cites W1523477938 @default.
• W2793649743 cites W1573309974 @default.
• W2793649743 cites W1970864665 @default.
• W2793649743 cites W1993072586 @default.
• W2793649743 cites W2001843840 @default.
• W2793649743 cites W2006436161 @default.
• W2793649743 cites W2009036226 @default.
• W2793649743 cites W2011609866 @default.
• W2793649743 cites W2017722755 @default.
• W2793649743 cites W2038875323 @default.
• W2793649743 cites W2045267651 @default.
• W2793649743 cites W2045475405 @default.
• W2793649743 cites W2051443179 @default.
• W2793649743 cites W2051646706 @default.
• W2793649743 cites W2059785103 @default.
• W2793649743 cites W2059821730 @default.
• W2793649743 cites W2065438642 @default.
• W2793649743 cites W2068227306 @default.
• W2793649743 cites W2068302119 @default.
• W2793649743 cites W2069409895 @default.
• W2793649743 cites W2083006206 @default.
• W2793649743 cites W2091799557 @default.
• W2793649743 cites W2093301069 @default.
• W2793649743 cites W2107204815 @default.
• W2793649743 cites W2109285747 @default.
• W2793649743 cites W2122465970 @default.
• W2793649743 cites W2141539055 @default.
• W2793649743 cites W2143435881 @default.
• W2793649743 cites W2157460080 @default.
• W2793649743 cites W2159567726 @default.
• W2793649743 cites W2162359545 @default.
• W2793649743 cites W2203017588 @default.
• W2793649743 cites W2215252198 @default.
• W2793649743 cites W2485905835 @default.
• W2793649743 cites W2549717966 @default.
• W2793649743 cites W2555219573 @default.
• W2793649743 cites W2582357041 @default.
• W2793649743 cites W2598024096 @default.
• W2793649743 cites W2621546725 @default.
• W2793649743 cites W2761108028 @default.
• W2793649743 doi "https://doi.org/10.1016/j.bbmt.2018.03.001" @default.
• W2793649743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29550628" @default.
• W2793649743 hasPublicationYear "2018" @default.
• W2793649743 type Work @default.
• W2793649743 sameAs 2793649743 @default.
• W2793649743 citedByCount "15" @default.
• W2793649743 countsByYear W27936497432019 @default.
• W2793649743 countsByYear W27936497432020 @default.
• W2793649743 countsByYear W27936497432021 @default.
• W2793649743 countsByYear W27936497432022 @default.
• W2793649743 countsByYear W27936497432023 @default.
• W2793649743 crossrefType "journal-article" @default.
• W2793649743 hasAuthorship W2793649743A5010413445 @default.
• W2793649743 hasAuthorship W2793649743A5021029688 @default.
• W2793649743 hasAuthorship W2793649743A5026301065 @default.
• W2793649743 hasAuthorship W2793649743A5029941019 @default.
• W2793649743 hasAuthorship W2793649743A5032050779 @default.
• W2793649743 hasAuthorship W2793649743A5036222762 @default.
• W2793649743 hasAuthorship W2793649743A5044253645 @default.
• W2793649743 hasAuthorship W2793649743A5056105964 @default.
• W2793649743 hasAuthorship W2793649743A5058287032 @default.
• W2793649743 hasAuthorship W2793649743A5060751609 @default.
• W2793649743 hasAuthorship W2793649743A5061611053 @default.
• W2793649743 hasAuthorship W2793649743A5068726940 @default.
• W2793649743 hasAuthorship W2793649743A5076234152 @default.
• W2793649743 hasAuthorship W2793649743A5088664989 @default.
• W2793649743 hasBestOaLocation W27936497431 @default.
• W2793649743 hasConcept C109159458 @default.
• W2793649743 hasConcept C126322002 @default.
• W2793649743 hasConcept C138496976 @default.
• W2793649743 hasConcept C141071460 @default.
• W2793649743 hasConcept C143998085 @default.
• W2793649743 hasConcept C15744967 @default.
• W2793649743 hasConcept C167135981 @default.
• W2793649743 hasConcept C187212893 @default.
• W2793649743 hasConcept C2776194465 @default.
• W2793649743 hasConcept C2777408962 @default.
• W2793649743 hasConcept C2778461978 @default.
• W2793649743 hasConcept C2780073493 @default.

• next