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• W2793829241 abstract "Describe the characteristics of chikungunya, dengue, and Zika in transplant recipients and immunocompromised hosts. Stem cell/bone marrow grafts, organs, and blood transfusions can transmit CHIKV/DENV/ZIKV infections, which are clinically similar, resembling influenza-like illness. Laboratory confirmation is necessary. In the acute phase, RT-PCR is preferred. DENV and ZIKV serology may cross-react. Delayed engraftment and extended viruria is observed in ZIKV+/HSCT recipients, while longer viremia is observed in DENV+/HSCT patients. Arbovirus persistence in organ tissues is generally unknown. Vaccine development is in early stages for CHIKV/ZIKV. No data is available to recommend the licensed DENV vaccine in transplant recipients. In endemic areas, the assessment of epidemiological risk is mandatory. Donor deferral for 120 days in suspected or confirmed ZIKV+ has been recommended, while CHIKV+ donors should wait 30 days. No deferral is recommended for DENV+ donors. CHIKV/DENV/ZIKV tests should be included in the differential of febrile neutropenia and other transplant syndromes. Reassessment of DENV serology is urgently needed. Prospective studies are necessary to determine the impact of CHIKV/DENV/ZIKV in this special population." @default.
• W2793829241 created "2018-03-29" @default.
• W2793829241 creator A5024143538 @default.
• W2793829241 creator A5065117953 @default.
• W2793829241 creator A5078990260 @default.
• W2793829241 date "2018-03-17" @default.
• W2793829241 modified "2023-10-09" @default.
• W2793829241 title "Chikungunya, Dengue, and Zika in Immunocompromised Hosts" @default.
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• W2793829241 doi "https://doi.org/10.1007/s11908-018-0612-2" @default.
• W2793829241 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5857271" @default.
• W2793829241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29551005" @default.
• W2793829241 hasPublicationYear "2018" @default.
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