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- W2793878533 abstract "Abstract Many cockroach species have adapted to urban environments, and some have been serious pests of public health in the tropics and subtropics. Here, we present the 3.38-Gb genome and a consensus gene set of the American cockroach, Periplaneta americana . We report insights from both genomic and functional investigations into the underlying basis of its adaptation to urban environments and developmental plasticity. In comparison with other insects, expansions of gene families in P. americana exist for most core gene families likely associated with environmental adaptation, such as chemoreception and detoxification. Multiple pathways regulating metamorphic development are well conserved, and RNAi experiments inform on key roles of 20-hydroxyecdysone, juvenile hormone, insulin, and decapentaplegic signals in regulating plasticity. Our analyses reveal a high level of sequence identity in genes between the American cockroach and two termite species, advancing it as a valuable model to study the evolutionary relationships between cockroaches and termites." @default.
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- W2793878533 date "2018-03-20" @default.
- W2793878533 modified "2023-10-14" @default.
- W2793878533 title "The genomic and functional landscapes of developmental plasticity in the American cockroach" @default.
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- W2793878533 doi "https://doi.org/10.1038/s41467-018-03281-1" @default.
- W2793878533 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5861062" @default.
- W2793878533 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29559629" @default.
- W2793878533 hasPublicationYear "2018" @default.
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