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• W2793990053 abstract "B6, an analog of curcumin, is a compound isolated from a traditional Chinese medicine Turmeric. In this paper, we aimed to explore the efficacy of B6 on diabetic nephropathy and the related mechanisms.The effects of B6 were studied on fast-blood glucose, serum creatinine, urea nitrogen, urine albumen/24 h, pathological changes of main organs, the levels of ACE2 and ACE2 mRNA in the rat model of diabetes induced by streptozotocin.The results showed that B6 treatment could reduce serum creatinine, urea nitrogen, urine albumen/24 h, decrease the level of AngII, improve the renal pathological changes in diabetic rats and increase the levels of ACE2 and ACE2 mRNA.These results suggested B6 could protect the renal function of diabetic rats. This study provided scientific basis for the further researches and clinical applications of B6." @default.
• W2793990053 created "2018-03-29" @default.
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• W2793990053 date "2018-03-26" @default.
• W2793990053 modified "2023-10-18" @default.
• W2793990053 title "Effects of a novel curcumin derivative on the functions of kidney in streptozotocin-induced type 2 diabetic rats" @default.
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• W2793990053 doi "https://doi.org/10.1007/s10787-018-0449-1" @default.
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