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- W2793991570 abstract "Proanthocyanidins (PCs) are naturally occurring polyphenolic compounds abundant in many vegetables, plant skins (rind/bark), seeds, flowers, fruits, and nuts. Numerous in vitro and in vivo studies have demonstrated myriad effects potentially beneficial to human health, such as antioxidation, anti-inflammation, immunomodulation, DNA repair, and antitumor activity. Accumulation of prooxidants such as reactive oxygen species (ROS) exceeding cellular antioxidant capacity results in oxidative stress (OS), which can damage macromolecules (DNA, lipids, and proteins), organelles (membranes and mitochondria), and whole tissues. OS is implicated in the pathogenesis and exacerbation of many cardiovascular, neurodegenerative, dermatological, and metabolic diseases, both through direct molecular damage and secondary activation of stress-associated signaling pathways. PCs are promising natural agents to safely prevent acute damage and control chronic diseases at relatively low cost. In this review, we summarize the molecules and signaling pathways involved in OS and the corresponding therapeutic mechanisms of PCs." @default.
- W2793991570 created "2018-03-29" @default.
- W2793991570 creator A5019723842 @default.
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- W2793991570 creator A5033788197 @default.
- W2793991570 creator A5053461832 @default.
- W2793991570 creator A5089806475 @default.
- W2793991570 date "2018-01-01" @default.
- W2793991570 modified "2023-10-01" @default.
- W2793991570 title "Proanthocyanidins against Oxidative Stress: From Molecular Mechanisms to Clinical Applications" @default.
- W2793991570 cites W1000973926 @default.
- W2793991570 cites W1132257252 @default.
- W2793991570 cites W1494529440 @default.
- W2793991570 cites W1506970858 @default.
- W2793991570 cites W1511419763 @default.
- W2793991570 cites W1543909914 @default.
- W2793991570 cites W177120868 @default.
- W2793991570 cites W1963814583 @default.
- W2793991570 cites W1964332547 @default.
- W2793991570 cites W1964606025 @default.
- W2793991570 cites W1967472138 @default.
- W2793991570 cites W1971903642 @default.
- W2793991570 cites W1972097754 @default.
- W2793991570 cites W1973141016 @default.
- W2793991570 cites W1975794822 @default.
- W2793991570 cites W1976599392 @default.
- W2793991570 cites W1981626955 @default.
- W2793991570 cites W1981786903 @default.
- W2793991570 cites W1987325894 @default.
- W2793991570 cites W1987638596 @default.
- W2793991570 cites W1991593801 @default.
- W2793991570 cites W1993952575 @default.
- W2793991570 cites W1995614749 @default.
- W2793991570 cites W1996521867 @default.
- W2793991570 cites W1998313754 @default.
- W2793991570 cites W1999369374 @default.
- W2793991570 cites W1999891390 @default.
- W2793991570 cites W2000565274 @default.
- W2793991570 cites W2001946904 @default.
- W2793991570 cites W2006441888 @default.
- W2793991570 cites W2007185373 @default.
- W2793991570 cites W2007653607 @default.
- W2793991570 cites W2007876572 @default.
- W2793991570 cites W2009429426 @default.
- W2793991570 cites W2009750549 @default.
- W2793991570 cites W2010154622 @default.
- W2793991570 cites W2016311545 @default.
- W2793991570 cites W2018436915 @default.
- W2793991570 cites W2019715806 @default.
- W2793991570 cites W2022687465 @default.
- W2793991570 cites W2025107493 @default.
- W2793991570 cites W2025639892 @default.
- W2793991570 cites W2025962043 @default.
- W2793991570 cites W2028294842 @default.
- W2793991570 cites W2031664674 @default.
- W2793991570 cites W2032100386 @default.
- W2793991570 cites W2034831207 @default.
- W2793991570 cites W2036552790 @default.
- W2793991570 cites W2037880347 @default.
- W2793991570 cites W2045405537 @default.
- W2793991570 cites W2047099862 @default.
- W2793991570 cites W2048888109 @default.
- W2793991570 cites W2051916173 @default.
- W2793991570 cites W2054550188 @default.
- W2793991570 cites W2055507834 @default.
- W2793991570 cites W2055584325 @default.
- W2793991570 cites W2058723405 @default.
- W2793991570 cites W2061995199 @default.
- W2793991570 cites W2064347448 @default.
- W2793991570 cites W2066613757 @default.
- W2793991570 cites W2069631422 @default.
- W2793991570 cites W2070100216 @default.
- W2793991570 cites W2070513297 @default.
- W2793991570 cites W2072193438 @default.
- W2793991570 cites W2072510816 @default.
- W2793991570 cites W2073300231 @default.
- W2793991570 cites W2076961963 @default.
- W2793991570 cites W2081699512 @default.
- W2793991570 cites W2087103387 @default.
- W2793991570 cites W2088631078 @default.
- W2793991570 cites W2090894363 @default.
- W2793991570 cites W2094837209 @default.
- W2793991570 cites W2095096262 @default.
- W2793991570 cites W2095325220 @default.
- W2793991570 cites W2096960090 @default.
- W2793991570 cites W2097174332 @default.
- W2793991570 cites W2099913359 @default.
- W2793991570 cites W2101602552 @default.
- W2793991570 cites W2102704816 @default.
- W2793991570 cites W2106092264 @default.
- W2793991570 cites W2108409617 @default.
- W2793991570 cites W2110856589 @default.
- W2793991570 cites W2111583532 @default.
- W2793991570 cites W2113129284 @default.
- W2793991570 cites W2119316269 @default.
- W2793991570 cites W2119331100 @default.
- W2793991570 cites W2120130716 @default.