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- W2794110004 abstract "OBJECTIVE To evaluate the importance of stone composition and crystallite size in the formation of ultimatestone burden. Crystallite is the smallest building block, which is unique in size and architecturefor each type of stone component. Currently, the knowledge about the clinical importance ofcrystallite size is very limited.METHODS The results of quantitative X-ray diffraction phase analysis performed on 286 kidney stonesextracted during endourological surgery or expelled spontaneously were retrospectively analyzed.Stone composition and crystallite size were determined and were compared to the burdenoccupying the pelvicalyceal system.RESULTS A total of 286 renal stones were analyzed. Stones were low burden and high burden in 242 and44 of cases, respectively. We observed statistically significant association of phosphates andurates with high-burden stones in contrast to oxalates, which formed mainly low-burden stones.Crystallite sizes were available for 179 stones. Large-sized crystallites of calcium oxalate mono-hydrate and hydroxyl apatite formed low-burden stones, whereas small-sized crystallites formedstaghorn stones. Struvite and urates had a uniform average size of crystallites.CONCLUSION Oxalatestoneshavestatisticallysignificantassociationwithsmallerstones,whereashigh-burdencalculiaresignificantly associated with urates and phosphates, especially the struvite type. The smaller the crystallitesize is to start with, the larger will be the ultimate stone burden. This rule is followed by calcium oxalatemonohydrate and Apatite minerals." @default.
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- W2794110004 date "2012-01-01" @default.
- W2794110004 modified "2023-09-26" @default.
- W2794110004 title "Endourology and Stones Crystallite Size—Is It a New Predictor for Renal Stone Burden?" @default.
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