FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2794127771> ?p ?o ?g. }

• W2794127771 endingPage "1214" @default.
• W2794127771 startingPage "1204" @default.
• W2794127771 abstract "Familial evaluation after a sudden death with negative autopsy (sudden arrhythmic death syndrome; SADS) may identify relatives at risk of fatal arrhythmias.This study aimed to assess the impact of systematic ajmaline provocation testing using high right precordial leads (RPLs) on the diagnostic yield of Brugada syndrome (BrS) in a large cohort of SADS families.Three hundred three SADS families (911 relatives) underwent evaluation with resting electrocardiogram using conventional and high RPLs, echocardiography, exercise, and 24-h electrocardiogram monitor. An ajmaline test with conventional and high RPLs was undertaken in 670 (74%) relatives without a familial diagnosis after initial evaluation. Further investigations were guided by clinical suspicion.An inherited cardiac disease was diagnosed in 128 (42%) families and 201 (22%) relatives. BrS was the most prevalent diagnosis (n = 85, 28% of families; n = 140, 15% of relatives). Ajmaline testing was required to unmask the BrS in 97% of diagnosed individuals. The use of high RPLs showed a 16% incremental diagnostic yield of ajmaline testing by diagnosing BrS in an additional 49 families. There were no differences of the characteristics between individuals and families with a diagnostic pattern in the conventional and the high RPLs. On follow-up, a spontaneous type 1 Brugada pattern and/or clinically significant arrhythmic events developed in 17% (n = 25) of the concealed BrS cohort.Systematic use of ajmaline testing with high RPLs increases substantially the yield of BrS in SADS families. Assessment should be performed in expert centers where patients are counseled appropriately for the potential implications of provocation testing." @default.
• W2794127771 created "2018-03-29" @default.
• W2794127771 creator A5004309542 @default.
• W2794127771 creator A5004742902 @default.
• W2794127771 creator A5007925883 @default.
• W2794127771 creator A5008286454 @default.
• W2794127771 creator A5010514675 @default.
• W2794127771 creator A5011045570 @default.
• W2794127771 creator A5011046385 @default.
• W2794127771 creator A5017916414 @default.
• W2794127771 creator A5020950019 @default.
• W2794127771 creator A5025087249 @default.
• W2794127771 creator A5029544703 @default.
• W2794127771 creator A5030646318 @default.
• W2794127771 creator A5045357003 @default.
• W2794127771 creator A5047158983 @default.
• W2794127771 creator A5056167269 @default.
• W2794127771 creator A5065358014 @default.
• W2794127771 creator A5065733928 @default.
• W2794127771 creator A5067054184 @default.
• W2794127771 creator A5069334671 @default.
• W2794127771 creator A5071974637 @default.
• W2794127771 creator A5080256028 @default.
• W2794127771 date "2018-03-01" @default.
• W2794127771 modified "2023-10-10" @default.
• W2794127771 title "The Diagnostic Yield of Brugada Syndrome After Sudden Death With Normal Autopsy" @default.
• W2794127771 cites W1540071197 @default.
• W2794127771 cites W1969311237 @default.
• W2794127771 cites W1989363116 @default.
• W2794127771 cites W2000208388 @default.
• W2794127771 cites W2008733212 @default.
• W2794127771 cites W2013627595 @default.
• W2794127771 cites W2013756939 @default.
• W2794127771 cites W2023636516 @default.
• W2794127771 cites W2041587009 @default.
• W2794127771 cites W2044779044 @default.
• W2794127771 cites W2051978340 @default.
• W2794127771 cites W2071084325 @default.
• W2794127771 cites W2078311582 @default.
• W2794127771 cites W2087350464 @default.
• W2794127771 cites W2087358757 @default.
• W2794127771 cites W2093544318 @default.
• W2794127771 cites W2097618980 @default.
• W2794127771 cites W2107496062 @default.
• W2794127771 cites W2109242434 @default.
• W2794127771 cites W2113359250 @default.
• W2794127771 cites W2119975602 @default.
• W2794127771 cites W2129087585 @default.
• W2794127771 cites W2131810639 @default.
• W2794127771 cites W2135302420 @default.
• W2794127771 cites W2139997566 @default.
• W2794127771 cites W2144237838 @default.
• W2794127771 cites W2147490644 @default.
• W2794127771 cites W2148858864 @default.
• W2794127771 cites W2149734574 @default.
• W2794127771 cites W2156109088 @default.
• W2794127771 cites W2166004591 @default.
• W2794127771 cites W2170016450 @default.
• W2794127771 cites W2170793251 @default.
• W2794127771 cites W2171418705 @default.
• W2794127771 cites W2347068500 @default.
• W2794127771 cites W2464776507 @default.
• W2794127771 cites W2474247475 @default.
• W2794127771 cites W2548446013 @default.
• W2794127771 cites W2609828677 @default.
• W2794127771 cites W2624319063 @default.
• W2794127771 doi "https://doi.org/10.1016/j.jacc.2018.01.031" @default.
• W2794127771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29544603" @default.
• W2794127771 hasPublicationYear "2018" @default.
• W2794127771 type Work @default.
• W2794127771 sameAs 2794127771 @default.
• W2794127771 citedByCount "76" @default.
• W2794127771 countsByYear W27941277712018 @default.
• W2794127771 countsByYear W27941277712019 @default.
• W2794127771 countsByYear W27941277712020 @default.
• W2794127771 countsByYear W27941277712021 @default.
• W2794127771 countsByYear W27941277712022 @default.
• W2794127771 countsByYear W27941277712023 @default.
• W2794127771 crossrefType "journal-article" @default.
• W2794127771 hasAuthorship W2794127771A5004309542 @default.
• W2794127771 hasAuthorship W2794127771A5004742902 @default.
• W2794127771 hasAuthorship W2794127771A5007925883 @default.
• W2794127771 hasAuthorship W2794127771A5008286454 @default.
• W2794127771 hasAuthorship W2794127771A5010514675 @default.
• W2794127771 hasAuthorship W2794127771A5011045570 @default.
• W2794127771 hasAuthorship W2794127771A5011046385 @default.
• W2794127771 hasAuthorship W2794127771A5017916414 @default.
• W2794127771 hasAuthorship W2794127771A5020950019 @default.
• W2794127771 hasAuthorship W2794127771A5025087249 @default.
• W2794127771 hasAuthorship W2794127771A5029544703 @default.
• W2794127771 hasAuthorship W2794127771A5030646318 @default.
• W2794127771 hasAuthorship W2794127771A5045357003 @default.
• W2794127771 hasAuthorship W2794127771A5047158983 @default.
• W2794127771 hasAuthorship W2794127771A5056167269 @default.
• W2794127771 hasAuthorship W2794127771A5065358014 @default.
• W2794127771 hasAuthorship W2794127771A5065733928 @default.
• W2794127771 hasAuthorship W2794127771A5067054184 @default.
• W2794127771 hasAuthorship W2794127771A5069334671 @default.

• next